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I-Raw Synephrine powder (97-07-5)

I-Synephrine ngokwemvelo ikhona izitshalo ze-citrus ezivela emndenini weRutaceae, yi-alkaloid sympathomimetic. I-Synephrine inezinto ezintathu ezahlukene ......


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum
Umthamo: 1370kg / inyanga

Incazelo

I-Raw Synephrine powder (ividiyo ye-97-07-5)

I-Raw Synephrine powder (97-07-5)

I-Raw Synephrine powder iyimvelo yamakhemikhali evamile eyenziwe ngabadlali kanye nalabo abafuna ukunciphisa isisindo ngenxa yemiphumela yayo ekukhiqizeni kwamandla emzimbeni. Kodwa-ke, lesi sakhi singenza futhi njenge-antioxidant kanye ne-anti-inflammatory agent futhi singaba nezinye izinzuzo ezibalulekile zezempilo.

I-Raw Synephrine powder yi-amine ye-biogenic. Itholakala emazingeni aphezulu ezinhlotsheni zezitshalo ze-citrus, njenge-orange enomuncu noma i-Seville orange (i-Citrus aurantium). Ukukhipha izithelo noma amapelisi alezi zitshalo kuye kwasetshenziselwa imithi yendabuko yaseShayina ukuphatha izinkinga zesisu nokudonswa kwemithi kwamakhulu eminyaka.

I-Raw Synephrine powder (Imininingwane ye-97-07-5)

Igama Product I-Raw Synephrine powder
Igama leKhemikhali Synephrine; I-Oxrinrine; I-P-Synephrine ;; I-Parasympatol; I-Sympaethamine
Brand NAme I-Yocon
I-Drug Class Amafutha alahlekile
CAS Inombolo 97-07-5
InChIKey I-YRCWQPVGYLYSOX-UHFFFAOYSA-N
I-molecular Fi-ormula C9H13NO2
I-molecular Weziyisishiyagalombili I-167.208 g / mol
IMisa ye-Monoisotopic I-167.095 g / mol
Ukuxuba Pi-oint 162 kuya ku-164 ° C
ukubila Point I-295.79 ° C (ukulinganisa okulinganiselwe)
I-Half Half-Life Ayikho idethi etholakalayo
Color I-white to off-white powder
Sukufaneleka Ayikho idethi etholakalayo
Sukuhlushwa Tukushisa Isiqandisisi
Aukuphikisana Ngokusobala izithako ezishisayo kakhulu ezishisayo zamafutha

I-Raw Synephrine powder (97-07-5) Incazelo

I-Synephrine, ebizwa nangokuthi, i-p-synephrine, isuke ivele i-alkaloid ngokwemvelo. Ingxenye enkulu ye-agonists ye-adrenergic i-p-synephrin, futhi ibhalwe phansi e-pharmacopoeia evela eNyakatho Yurophu naseJalimane.Ikhona emikhiqizweni edakamizwa evunyelwe njenge-neo-synephrine, i-analog yayo ephindaphindiwe. i-p-synephrine kanye ne-m-synephrin baziwa ngemiphumela yabo ehlala isikhathi eside ye-adrenergic uma kuqhathaniswa ne-norepinephrine. Ingasetshenziselwa ukwelashwa kwemitholampilo ye-asthma ye-bronchial, hypotension, ukuwa, ukushaqeka, kanye ne-hypotension orthostatic; ukuthuthukisa umzimba; futhi ukwelashwa kwezinkinga zokugaya ukudla njenge-indigestion, ukuvuvukala kwesibindi, i-phlegm, ne-ptosis.

Emazweni angaphandle, i-raw synephrine powder iye yafunwa ngabagijimi nalabo abafuna ukulahlekelwa isisindo ngenxa yemiphumela yayo emandleni omzimba. I-Synephrine isetshenziswa ekwelapheni ukukhuluphala ngokweqile ukwandisa ikhalori ukusetshenziswa kanye ne-oxidation fat, kanye nokunciphisa ukucindezeleka okuncane okubangelwa ukukhuluphala. Kodwa-ke, lesi sakhi singenza futhi njenge-antioxidant kanye ne-anti-inflammatory agent futhi singaba nezinye izinzuzo ezibalulekile zezempilo.

I-Raw Synephrine powder i-amine ye-biogenic. Itholakala emazingeni aphezulu ezinhlotsheni zezitshalo ze-citrus, njenge-orange enomuncu noma i-Seville orange (i-Citrus aurantium). Ukukhipha izithelo noma amapelisi alezi zitshalo kuye kwasetshenziselwa imithi yendabuko yaseShayina ukuphatha izinkinga zesisu nokudlulela kwamakhulu eminyaka. Njengamanje, i-p-synephrine isetshenziswa kakhulu emithi, imithi, isiphuzo nezinye izimboni.

I-Synephrine powder (97-07-5) Indlela Yokusebenza

Imiphumela ye-cardiavascular ligands ihlotshaniswa ne-adrenergic receptor ebophayo. Ngokuvamile, lapho i-ligands ibophezela ku-α-adrenergic receptors, i-vasoconstriction ivela, futhi uma ibophezela ku-receptors ye-β1-adrenergic, inkontileka ye-cardiovascular kanye nokwanda kwesilinganiso senhliziyo. Ucwaningo lubonisa ukuthi i-synephrine powder ibophezela ku-β3-adrenergic receptors, okwenza kube nokwanda kwamandla omzimba wokuphula amafutha. Ukubopha ama-receptor β3-adrenergic akuthinti ithonya lenhliziyo noma umfutho wegazi. Futhi, ngoba i-synephrine ibonisa kancane noma ayikho imbopho e-α1-, i-α2-, β1-, ne-β2-adrenergic receptors futhi ayibonakali ukuthi ingabonakali ngendlela engavamile, imiphumela ye-cardiovascular, njengokwanda kwenani lenhliziyo nokucindezelwa kwegazi, akuzona okuhlangenwe nakho okujwayelekile okusetshenziselwa, ngokungafani nezinye izinhlobo ze-phenylethylamine nezidakamizwa ze-phenylpropanolamine. Izinguquko ezincane zesakhiwo ziholela ekuhlukeni okukhulu kwe-adrenergic receptor ebopha futhi kamuva ikhono lokukhiqiza imiphumela ye-cardiovascular.

I-Synephrine iphinde ithuthukise ukusetshenziswa komzimba we-carbohydrate ngokukhiqiza amandla amaningi ngesimo se-ATP.49-52 Ihambisa ukutholakala kwamaselula kweglucose kumaseli omzimba, kanye ne-glycogenolysis, i-gluconeogenesis, i-glycolysis, ne-oxygen uptake. Ukubandakanya kokubili i-calcium ion kanye ne -AMP nge-adrenergic receptors kuye kwaboniswa ukuthi kuhileleke kulezi zinqubo ze-biochemical, okubonisa ukuthi kuhileleke kwezindlela eziningi.

Ngaphandle kwalokho, ukusetshenziswa kwe-Synephrine powder kuzovimbela ukusebenza kwe-NF-kB. Lesi sici siyisihluthulelo ekwenzeni izifo ezinokuvutha njenge-asthma. Ukusetshenziswa kwe-Synephrine kuye kwatholakala ukuthi kuthinta isenzo se-eotaxin-1 hormone ngokuyinhloko. Lokhu kuvimbela ukuhamba kwe-eosinophil endaweni evulekile.

Nakuba kungabonakaliswa kahle ngokuhlolwa, ukusetshenziswa kwe-Synephrine powder kutholakale ukuvimbela isenzo se-acetylcholineterase. Lezi zimakhemikhali ziyaziwa ukuthi zibangela isifo se-Alzheimer.

Isicelo se-Synephrine powder (97-07-5)

▪ Ukuthuthukisa ukusebenza komzimba

▪ Ukwelapha isifo sikashukela

▪ Ukusiza ukulahlekelwa isisindo

▪ Ukunciphisa ukwesaba ngaphambi kokuhlinzwa

▪ Ukwelapha izifo zesikhumba ezinjengezinyosi, unyawo lomdlali, kanye ne-jock itch.

▪ Thuthukisa amazinga we-Mood and Energy

Kunconywe i-Synephrine powder (97-07-5) Isilinganiso

Amanani ajwayelekile we-Synephrine powder yi-50-100mg ngosuku nosuku lwe-30-40 ngaphambi kokusebenza. Futhi, kungcono ukuthathwa into yokuqala ekuseni noma imizuzu engu-15 - 30 ngaphambi kokuzivocavoca. I-Synephrine powder kufanele ithathwe ngamanzi ngaphambi kokuzivocavoca.

Izinzuzo ze-Synephrine powder (97-07-5)

♦ Ucwaningo (DB-RCT) lwamadoda we-12 lubonise ukuthi i-synephrine powder ethathwe imizuzu ye-45 ngaphambi kokuzivocavoca kwandisa inani lokuphindaphinda kanye nomthwalo wesisindo esiphezulu uma kwenziwa ama-squats kuqhathaniswa ne-placebo.

♦ Ucwaningo lwangaphambi kwesikhathi lubonisa ukuthi ukuphuza itiye okwenziwa amaqabunga e-Indian snakeroot nesithelo se-orange obabayo ngezinyanga ze-4 kubonakala kunciphisa amazinga kashukela egazini kubantu abanesifo sikashukela.

♦ Inhlanganisela ye-synephrine, i-caffeine, ne-St. John's wort ingasiza ekunciphiseni isisindo uma isetshenziselwa ukudla okuphansi kwekhalori nokuzivocavoca.

♦ Ucwaningo (DB-RCT) lwezihloko ze-10 ezinikezwe i-50 mg ye-synephrin kubonise ukuthi lezi zihloko zishisa ama-calories angu-65 ngaphezu kwabahlanganyeli abanikezwa indawobo emaminithini wokuqala we-75 ngemuva kokuthatha isengezo.

♦ Ucwaningo lubonisa ukuthi ukuthatha ama-orange omuncu amahora amabili ngaphambi kokuhlinzwa kunciphisa ukwesaba.

♦ Amafutha amancane ama-orange, aqukethe i-synephrin ngaphezu kwezinye izithako ezisebenzayo, ocwaningweni olulodwa lweziguli ze-60, ukuthuthukiswa kwezifo zesikhumba (amazinyawo, umzimba / isikhumba) ku-2 kuya kuma-3 amasonto ngaphezulu kwe-80% yabathintekayo.

♦ Amantombazane anezibonakaliso zakudala zokucindezeleka, kufaka phakathi izinkinga zokulala kanye nezinguquko ekudleni, enza okubi nakakhulu ekuphenduleni izenzakalo ezicindezelayo, njengokuphoqeleka ukuba ugejime, kunezinja eziphilile. Ucwaningo olulodwa lubonise ukuthi amagundane adle ama-synephrine powderwere akwazi ukugibela isikhathi eside, okukhombisa amazinga aphezulu namanethiwekhi

♦ Ucwaningo olulodwa lwe-laboratory lubonise ukuthi i-synephrine powder ivimbele ukukhula kwamabhaktheriya amanye kuhlanganise no-E. coli, okungaholela ekudleni kokudla, kanye ne-Staphylococcus aureus, engabangela izifo zesikhumba.

♦ Ucwaningo olwenziwe ngokusebenzisa izingulube ze-guinea lubonisa ukuthi i-synephrine inciphisa ukuphazamiseka kwemisipha ebushelelezi ku-trachea, uphawu oluhambisana nokukhwehlela. U-Synephrine naye wanciphisa izimpawu zesifo se-asthma ezenzeka lapho izilwane zinikezwa i-histamines.

♦ Emagundini okulimala kwamaphaphu, i-synephrine inciphise inani lamaseli avuthayo kanye namactokines okuvuthayo TNF-alpha ne-IL-6, ngenkathi ukwandisa i-IL-10 ephikisayo.


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I-Shangke Chemical yinkampani ephezulu echwepheni ezisebenzayo ezizimele eziphambili zokwelapha (APIs). Ukuze ulawule ikhwalithi ngesikhathi sokukhiqiza, inqwaba yabachwepheshe abanolwazi, imishini yokukhiqiza yokuqala kanye nama-laboratories yiwona amaphuzu ayisihluthulelo.

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