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I-Raw Synephrine HCL powder (5985-28-4)

I-Synephrine HCL powder iyinhlangano ye-alkaloid yamakhemikhali eyenzeka ngokwemvelo itholakala izitshalo futhi isetshenziselwa ukusetshenziswa njenge-supplement ......


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum
Umthamo: 1450kg / inyanga

Incazelo

Ividiyo yama-Raw Synephrine HCL (5985-28-4)

Imininingwane yama-Raw Synephrine HCL (5985-28-4)

Igama Product I-Raw Synephrine HCL powder
Igama leKhemikhali I-Synephrine hydrochloride; 5985-28-4; 4- (1-Hydroxy-2- (methylamino) ethyl) phenol, i-hydrochloride;
Brand NAme I-Yocon
I-Drug Class Amafutha alahlekile
CAS Inombolo 5985-28-4
InChIKey I-COTCEGYSNTWJQV-UHFFFAOYSA-N
I-molecular Fi-ormula C9H14ClNO2
I-molecular Weziyisishiyagalombili I-203.666 g / mol
IMisa ye-Monoisotopic I-203.071 g / mol
Ukuxuba Pi-oint I-147-150 ° C
ukubila Point I-341.10 ° C. @ 760.00 mm Hg (est)
I-Half Half-Life Ayikho idethi etholakalayo
Color I-white to off-white powder
Sukufaneleka Ayikho idethi etholakalayo
Sukuhlushwa Tukushisa Isiqandisisi
Aukuphikisana Ngokusobala izithako ezishisayo kakhulu ezishisayo zamafutha

I-Raw Synephrine i-hcl i-powder (5985-28-4) Incazelo

I-Raw Synephrine HCL i-powder iyinhlangano yamakhemikhali e-alkaloid eyenzeka ngokwemvelo itholakala izitshalo futhi ikhishwe ukuze isetshenziswe njengesengezo. Ngezinye izikhathi i-Synephrine ibizwa ngokuthi 'i-orange ebabayo' njengoba itholakala kuma-oranges amancane. Eqinisweni, itholakale ngokwemvelo emgodini we-orange, yingakho ibiwa ngokuthi i-orange enomuncu. Inhlanhla ye-orange manje isetshenziselwa inombolo efana nezinkinga ezifanayo kanye nezinye izinkinga zanamuhla zithinta ukulahlekelwa isisindo futhi njengesizo empini ngokumelene nonyawo lomdlali. ingenye yezinhlanganisela eziyinhloko e-orange enomuncu futhi ecatshangwa ukuthi iyisisekelo semfanelo yokuphulukisa yesitshalo I-Raw Synephrine HCL powder, ngokusobala ukuthi amafutha afisa kakhulu ama-ingredients.Synephrine itholakala kuma-oranges, futhi uma unayo, ungakwazi bazuze kuzo zonke izindlela ezahlukene.

Njengesithako sokuncedisa ukudla, i-synephrine HCL powder cishe iphephile kubantu abadala kakhulu uma isetshenziswe kahle. Noma kunjalo, kunemiphumela emibi emnene phakathi kwabasebenzisi abathwala kakhulu i-synephrine hcl. I-Synephrine iyisisusa, ngakho-ke kubalulekile ukuqala esilinganisweni esincane ukuhlola ukubekezelelana. I-synephrine excessive ngokweqile ingabangela ukwanda okusheshayo kwegazi, ama-arrhythmiya enhliziyo, ukukhukhula kwesikhumba, ukuhlala, ukuphumula, ukukhathazeka, izinkinga zokuphefumula, isizungu, ikhanda, ukuthuthumela, ishukela ephansi yegazi kanye nokungalingani kweshukela egazini, ubuhlungu besisu, i-nausea, nesifo sohudo, ikakhulukazi kuhlanganiswe nezinye izikhuthazo.

I-Synephrine i-hcl powder (5985-28-4) Indlela Yokusebenza

Imiphumela ye-cardiavascular ligands ihlotshaniswa ne-adrenergic receptor ebophayo. Ngokuvamile, lapho i-ligands ibophezela ku-α-adrenergic receptors, i-vasoconstriction ivela, futhi uma ibophezela ku-receptors ye-β1-adrenergic, inkontileka ye-cardiovascular kanye nokwanda kwesilinganiso senhliziyo. Ucwaningo lubonisa ukuthi i-synephrine hcl powder ibophezela ku-β3-adrenergic receptors, okwenza kube nokwanda kwamandla omzimba wokuphula amafutha. Ukubopha ama-receptor β3-adrenergic akuthinti ithonya lenhliziyo noma umfutho wegazi. Futhi, ngoba i-synephrine ibonisa kancane noma ayikho imbopho e-α1-, i-α2-, β1-, ne-β2-adrenergic receptors futhi ayibonakali ukuthi ingabonakali ngendlela engavamile, imiphumela ye-cardiovascular, njengokwanda kwenani lenhliziyo nokucindezelwa kwegazi, akuzona okuhlangenwe nakho okujwayelekile okusetshenziselwa, ngokungafani nezinye izinhlobo ze-phenylethylamine nezidakamizwa ze-phenylpropanolamine. Izinguquko ezincane zesakhiwo ziholela ekuhlukeni okukhulu kwe-adrenergic receptor ebopha futhi kamuva ikhono lokukhiqiza imiphumela ye-cardiovascular.

I-Synephrine i-hcl powder iphinde ithuthukise ukusetshenziswa komzimba we-carbohydrate ngokukhiqiza amandla amaningi ngendlela ye-ATP.49-52 Insiza ukutholakala kwamaselula kweglucose kumaseli emisipha, kanye ne-glycogenolysis, i-gluconeogenesis, i-glycolysis, ne-oxygen uptake. Ukubandakanya kokubili i-calcium ion kanye ne -AMP nge-adrenergic receptors kuye kwaboniswa ukuthi kuhileleke kulezi zinqubo ze-biochemical, okubonisa ukuthi kuhileleke kwezindlela eziningi.

Ngaphandle kwalokho, ukusetshenziswa kwe-Synephrine hcl powder kuzovimbela ukusebenza kwe-NF-kB. Lesi sici siyisihluthulelo ekwenzeni izifo ezinokuvutha njenge-asthma. Ukusetshenziswa kwe-Synephrine powder kutholakale nokuthi kuthinta isenzo se-eotaxin-1 hormone ngokuyinhloko. Lokhu kuvimbela ukuhamba kwe-eosinophil endaweni evulekile.

Nakuba kungabonakaliswa kahle ngokuhlolwa, ukusetshenziswa kwe-Synephrine hcl powder kutholakale ukuvimbela isenzo se-acetylcholineterase. Lezi zimakhemikhali ziyaziwa ukuthi zibangela isifo se-Alzheimer.

Izinzuzo we-Synephrine i-hcl i-powder (i-5985-28-4)

  • I-Synephrine hcl yokulahlekelwa kwesisindo
  • I-Synephrine hcl ukusiza ukulahlekelwa ukudla
  • I-Synephrine hcl yandisa ukutholakala kwe-glucose emisipha engcono
  • I-Synephrine hcl i-glycogenesis yezinsiza ezingalungile
  • I-Synephrine hcl isiza ekulawuleni isifo sikashukela
  • I-Synephrine hcl ithuthukise ukugaya
  • I-Synephrine hcl inciphisa ukwesaba ngaphambi kokuhlinzwa
  • I-Synephrine hcl ithuthukisa ama-mood namazinga wamandla
  • Synephrine hcl ukusiza ukulawula amabhaktheriya ayingozi
  • I-Synephrine hcl kusiza ukuvuvukala okuncishisiwe

Kunconywe i-Synephrine i-hcl i-powder (5985-28-4) Isilinganiso

Isilinganiso se-Synephrine hcl esivame ukusetshenziswa kakhulu sine-100mg ngosuku. Lokhu kubhekwa njengesilinganiso esanele sokukwazi ukulahlekelwa isisindo. Kodwa-ke, inani eliphakanyisiwe lokuthi ngisho nabasebenzisi abalimi akumele badlule i-200mg ngosuku. Noma yini engaphezu kwalolu phawu kubhekwa njengobuthi futhi iyobeka umuntu engozini yokuthola umshwalense wemiphumela emibi ebulalayo ehambisana nokuvuselelwa kokusetshenziswa. Kunconywa, ukuqala, i-10 ku-20mg ukuqinisekisa ukuthi i-Synephrine hcl powder ihambelana nomzimba wakho. Ngemuva kokuthatha le mithi yokuqala, kufanele uthathe isikhathi sokuhlola impendulo yomzimba ekugcineni. Uma konke kuhle, isilinganiso sesibili se-20mg singezwa ngemva kwamahora amabili. Ngaphandle kwalokho, isikhathi sokuphepha esiphephile sithatha i-Synephrine hcl powder kanye namahora amabili.

Okuqhamuka uma udla imishanguzo we-Synephrine i-hcl i-powder (i-5985-28-4)

Ukusetshenziswa kwe-Synephrine nakho kuhambisana nemiphumela emibi njenganoma imuphi omunye umuthi. Uma omunye umbhangqwana usebenzisa ukusetshenziswa kwe-synephrine hcl ndawonye ne-caffeine. futhi iza neminye imiphumela emibi. Okulandelayo yiminye imiphumela emibi ejwayelekile:

  • Umfutho wegazi ophezulu.
  • Isifo senhliziyo.
  • Ukushaya kwenhliziyo okungavamile.
  • Ukufa uma kusetshenziselwa isilinganiso esiphezulu ngaphambi kokuhlinzwa.
  • Ama-hallucinations / kwengqondo
  • I-coronary spasms kanye ne-thrombosis
  • Ukuphazamiseka kwengqondo yenhliziyo (fibrillation ye-ventricular)
  • Ukunciphisa ubukhulu bomzimba (rhabdomyolysis)
  • Ukuhluleka kwezinso
  • Ama-clots egazi
  • Umonakalo wamagciwane ngenxa yocindezelo eyengeziwe emisipha (i-compartment syndrome)
  • Ubuhlungu besifuba (i-angina ehlukile)
  • Stroke


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Okubhekiselweyo nokuhlungwa komkhiqizo

I-Synephrine HCL isebenza kanjani emzimbeni wakho?

Okubhekwayo

  1. U-Akhlaghi, M., Shabanian, G., Rafieian-Kopaei, M., Parvin, N., Saadat, M., no-Akhlaghi, uMnu Citrus ubuqhakabhakeni bokuqala kanye nokukhathazeka kwangaphambili. IsiBr BrasAnestesiol. 2011; 61 (6): 702-712.
  2. Bent, S., Padula, A., neNeuhaus, J. Ukuphepha nokusebenza kwe-citrus aurantium yokulahlekelwa isisindo. Am.J.Cardiol. 11-15-2004; 94 (10): 1359-1361
  3. Campbell-Tofte, JI, Molgaard, P., Josefsen, K., Abdallah, Z., Hansen, SH, Cornett, C., Mu, H., Richter, EA, Petersen, H, Norregaard, JC, noWinther, Ucwaningo lwama-pilo olwenziwa nge-K. Randomised and double blinded by therapy and anti-diabetes of tea Rauvolfia-Citrus, njengoba lisetshenziselwa imithi yendabuko yaseNigeria. J Ethnopharmacol. 1-27-2011; 133 (2): 402-411.
  4. R. Costa, MBA Glória, kuyi-Encyclopedia of Food Sciences and Nutrition (Edition Second), i-2003
  5. Ghanim H, Sai CL, i-Upadhyay M. et al. Ijusi le-Orange lingafaki umphumela wokushisa ophezulu we-fat fat, high-carbohydrate ukudla futhi kuvimbele ukwanda kwe-endotoxin nokukhulumisana kwe-receptor efana ne-Toll. Amer J Clin Nutriti. 2010; 91: 940-949
  6. AmaSJ. Ukuhlolwa kwemibiko emibi yomcimbi ehambisana nayo I-Citrus aurantium(orange orange) kusuka April 2004 kuya Okthoba 2009.
  7. UDragull K, Breksa AP, uKayin B. Synephrine okuqukethwe kwamanzi kusuka ku-Satsuma mandarins (Citrus unshiuMarcovitch). J Agric.Food Chem. 2008; 56: 8874-8878
  8. I-Roman MC, uBetz JM, uHildreth J. Ukunqunywa kwe-synephrin ngezinsimbi ezimbi eziluhlaza, ama-extracts, kanye nezithako zokudla nge-chromatography yomswakama ene-ultraviolet ukubona: ukuqinisekiswa okukodwa kwe-laboratory. J Amer Org Anal Chemists Int. 2007; 90: 68-81
  9. I-Mercolini L, uMandrioli R, uTrere T. et al. Ukuhlaziywa okusheshayo kwe-CE kwe-amrenergic amines ezingxenyeni ezahlukene I-Citrus aurantiumizithelo nezithako zokudla. J Sep Sci. 2010; 32: 1-8
  10. I-Haaz S, i-Fontaine KR, i-Cutter G, i- Limdi N. et al. I-Citrus aurantiumfuthi synephrine alkaloids ekwelapheni ukwedlula ngokweqile nokukhuluphala: isibuyekezo. Ukukhuluphala kukaMfundisi 2006; 7: 79-88
  11. Higgins, JP, Tuttle, TD, and Higgins, CL Amanzi iziphuzo: okuqukethwe nokuphepha. I-Mayo Clin Proc. 2010; 85 (11): 1033-1041.
  12. I-Kaats, i-GR, i-Miller, i-H., i-Preuss, i-HG, ne-Sto, i-SJ A 60day isifundo sokuphepha esiphezulu se-placebo esiphathelene ne-placebo eshicilela i-Citrus aurantium (i-orange orange). I-Chem Toxicol Yokudla. 2013; 55: 358-362.
  13. Lynch B. Ukubukeza kokuphepha kwe-p-synephrine ne-caffeine. Umbiko we-Intertek-Cantox, i-2013; i-1-20.
  14. Ukuhlolwa kwezempilo kwemikhiqizo yezemidlalo kanye nokulahlekelwa kwesisindo equkethe i-synephrine ne-caffeine BfROpinion No. 004 / 2013, ye-16 November 2012

I-Shangke Chemical yinkampani ephezulu echwepheni ezisebenzayo ezizimele eziphambili zokwelapha (APIs). Ukuze ulawule ikhwalithi ngesikhathi sokukhiqiza, inqwaba yabachwepheshe abanolwazi, imishini yokukhiqiza yokuqala kanye nama-laboratories yiwona amaphuzu ayisihluthulelo.

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