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I-Raw YK-11 powder (431579-34-9)

I-YK-11 powder ingokwesigaba se-androgen receptor modulators (SARM) ekhethiwe. Ngokuyinhloko, yiziphi i-YK11 ezenza ngokukhetha ......


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum
Umthamo: 1470kg / inyanga

Incazelo

I-Raw YK-11 powder (431579-34-9) ividiyo

I-Raw YK-11 powder (431579-34-9) Incazelo

I-YK11, eyaziwa nangokuthi i-Myostine, ibhekwa njengenye ye-SARM enamandla emakethe. I-synthetic steroidal ekhetha i-androgen receptor modulator. Isidakamizwa sinomsebenzi we-anabolic ku-vitro ku-C2C12 myoblasts futhi ibonisa amandla amakhulu kune-dihydrotestosterone (DHT) kulokhu. I-YK11 nayo i-Myostatin inhibitor. bangakusiza ukuba uthole imisipha futhi ulahlekelwe amafutha.

I-Raw YK-11 powder (431579-34-9) Siziqu

Igama Product I-Raw YK-11 powder
Igama leKhemikhali YK11, (17a, 20E) -17,20 - [(1-Methoxyethylidene) bis (oxy)] - 3-oxo-19-norpregna- 4,20-diene-21-carboxylic Acid Methyl Ester; YK11 ((17α, 20E) -17,20 - [(1-methoxyethylidene) bis- (oxy)] - 3-oxo-; i-DNA (i-Terrabacter strain YK11 16S i-rRNA isici segciwane); GenBank AB070463
Brand NAme Ayikho idatha etholakalayo
I-Drug Class Ama-SAR
CAS Inombolo 431579-34-9
InChIKey I-KCQHQCDHFVGNMK-DEIKBOPOSA-N
I-molecular Fi-ormula C25H34O6
I-molecular Weziyisishiyagalombili 430.53386
IMisa ye-Monoisotopic I-430.236 g / mol
Ukuxuba Pi-oint I-190-200 ° C
Fukuvuselela kabusha Pi-oint Ayikho idatha etholakalayo
I-Half Half-Life Amahora we-6-10, kuye ngokuthi umuntu ngamunye
Color Ukuqina okumhlophe
Sukufaneleka I-Propylene Glycol, iDMSO, i-Ethanol
Sukuhlushwa Tukushisa Ukushisa kwamakamelo
I-Raw YK-11 powder Aukuphikisana I-Androgen Receptor Modulator ekhethiwe, i-Myostatin Inhibitor

I-Raw Raw Raw YK-11 (431579-34-9) Incazelo

Abasebenzisi abaningi bacabanga ukuthi i-YK11 iyisihluthulelo sokuvula ikhono eligcwele lomzimba nokufeza ukuzuza kwemisipha okusheshayo nemiphumela emibi embalwa. I-YK11 ibonakala i-super-SARM esekelwe ekubuyekezweni, kanti empeleni, lesi sidakamizwa AKUSI-SARM ejwayelekile. Lesi sihloko sidiliza isayensi nokubuyekezwa ukukunikeza umbono ocacile wokuthi yini ongayilindela kusuka kule hybridi yeSARM-steroid, enezingozi nemiphumela emibi.

Iphinde ithi i-YK11 inamandla okunciphisa umsebenzi we-myostatin, okwenza kube yi-inhibitor ye-myostatin. I-YK-11 i-sarm nakanjani iyisinye seziqine kunazo zonke laphaya. Awukwazi ukuqhathanisa i-YK ne-LGD-4033 noma enye i-SARM ngenxa yokuthi iqinile kangakanani.

Kodwa-ke, yize i-YK-11 i-powder eluhlaza iqina ngamandla kakhulu khumbula ukuthi kube khona izifundo ezimbalwa kuphela ezenziwe ngalesi sakhi. Lesi sizathu esiyinhloko abantu abaningi kubonakala sengathi bahamba nge-SARM njengo-Ostamuscle, RAD-140 noma i-GW-501516.

I-YK11 ithola isithakazelo kubakhi bomzimba ngenxa yikhono layo lokwakha ngokushesha imisipha ngemiphumela emibi kakhulu, kufana nama-SARM ahlukahlukene. Isakhiwo se-YK11 sihlukile. I-molecule ye-YK ihlanganyela kaningi ngokufanayo ne-steroids kune-SARM, nakuba ijwayele ukufakwa ngephutha egcekeni elifanayo njengawo wonke amanye ama-SARM angenayo i-steroidal.

Esinye isifundo seselula sikhombisa ukuthi i-YK11 ikhulisa ubuningi besisipha. Abacwaningi bathola ukuthi kwandisa amaprotheni follistatin (a myostatin inhibitor).

I-YK11 ingathuthukisa impilo ye-bone. Esicwaningweni samaseli amathambo, i-YK11 yakhula amazinga we-protini yokwakha amathambo.

Abanye abakhi bomzimba abaye bahlola i-YK11 babika ukuzuza kwemisipha emihle nokulahlekelwa kwamafutha nemiphumela emibi kakhulu. Kodwa-ke, okwamanje ayikho isilwane noma izifundo zabantu ze-YK11 nokuphepha kwayo akucacile.

I-YK-11 powder emifushane (431579-34-9) Indlela Yokusebenza

I-YK11 inesakhiwo samakhemikhali esifanayo ku-DHT futhi lokhu kuboniswa ngendlela ebophezela ngayo i-androgen receptors. Umzimba ukhiqiza i-DHT ngokwemvelo ngenhloso yokukhuthaza impilo ye-prostate, ukukhula kwezinwele, nokuthuthukiswa okufanele ukukhulelwa.

Uma ngabe sifunda ekilasini i-YK11 njengo-SARM ngakho-ke kuyoba yindlela enamandla kunazo zonke futhi enamandla kakhulu emakethe. Lokhu kungenxa yokuthi isebenze kuphela i-androgen receptors ingxenye, okubangela umsebenzi we-andogengen wokudutshulwa ophahleni. Ngaphezu kwalokho, i-YK11 iyaziwa ngokuthi i-myostatin inhibitor.

Abacwaningi benza ucwaningo lweseli ukuthola ukuthi lisebenza kanjani ukwakha imisipha. Imiphumela ibonisa ukuthi ihlose ukwandisa ama-follistatin amazinga. I-Follistatin enye eyenzeka ngamaprotheni emzimbeni womuntu osiza ukugcina i-myostatin isheke. I-Myostatin iyi-hormone eyomsebenzi wayo ukuvimbela ukukhula kwemisipha engavamile.

Kuze kube manje, kuphela i-YK11 powder eluhlaza enekhono lokuvimbela i-myostatin.

Ubufakazi obengeziwe bukhombisa ukuthi i-YK11 ingakhuthaza nokukhula kwethambo ngokuphazamisa isango elisebenza njengeDHT.

Izinzuzo of Raw YK11 powder (431579-34-9)

Ukwandisa Ubukhulu Bamasipha

Nakuba i-YK11 engeyona i-SARM ngayinye, inekhono elimangalisayo lokugqugquzela ukukhula komzimba. Kuthiwa kunamandla njengo-S23.

Lokhu kungenxa yokuthi ngokwemvelo kukhulisa ama-follistatin amazinga okwenza ngcono amandla omzimba wakho wokukhiqiza amangqamuzana omzimba. I-Follistatin ibuye ikwazi ukucindezela i-myostatin, ngaleyondlela ikuvula kuze kube khona ukukhula okungapheli kwemisipha. Kodwa uma imiphumela ye-follistatin ivinjelwa nganoma iyiphi indlela, ukuvimbela kwe-myostatin akunakwenzeka, okwenza ukuthi i-YK11 ingasebenzi.

Akufanele uzwakale njengerekhodi ephukile kodwa azikho izifundo zesintu noma zezilwane ukubuyisela idatha kule nkampani.

Konke esinakho ubufakazi be-anecdotal ngokusekelwe ekubuyekezweni komzimba kumasimu enethiwekhi. Lokho abasitshelayo ukuthi bakwazi ukubhekana nokunciphisa amanoni okuphawulekayo futhi ama-15 lbs ayesezingeni elimnandi le-muscle elizuzayo ngesikhathi esincane.

Uqinisa Amatshe

Ama-hormone wezocansi abalulekile ekugcineni amathambo aqinile futhi anempilo. Ubufakazi obutholakalayo bubonisa ukuthi i-YK11 i-powder eluhlaza ingakhuphula amandla amathambo ngokuzibophezela ezikwamukeli ze-androgen, okufana nalokho okushiwo ama-SAR amaningi.

I-YK11 ingakwandisa inani le-PKB esebenzayo (i-protein kinase B) ekhona emangqamuzaneni omzimba okusiza ukukhula kwamaseli esithambo.

Asingakhohlwa ukuthi ufuna ukuba nemisipha enamandla, enempilo namathambo ukugwema ukuqhuma. Kungase kusize nalokhu futhi ngoba kuyasebenza kakhulu ekwakheni imisipha, ukusekela impilo ye-bone nokunciphisa imiphumela ye-bone fragility.

I-Raw YK-11 ephakanyisiwe (431579-34-9) Isilinganiso

Ama-bodybuilders asebenzise i-YK11 powder eluhlaza athi ukuwuthatha emingeni ye-10 kuya ku-15 mg ngosuku usebenza kahle kubo. Abanye baye babika imiphumela emihle ku-5 mg ngosuku. Abasebenzisi abaningi bawujikeleza nge-4 kumaviki angu-8. Uzothola nabasebenzisi abafaka ama-SARM ahlukene ndawonye.

Okuqhamuka uma udla imishanguzo of Raw YK-11 powder (431579-34-9)

▲ Kuze kube manje, izifundo zeselula kuphela zenziwe ku-YK11.

Ayikho ubufakazi bokutholwa komzimba noma ngisho nezifundo zezilwane ukubuyisela noma yiziphi izimangalo ezenziwa mayelana nomuthi.

Lokhu kuzokukwenza ucabange kabili ngokucwaninga ngalesi sakhi. Mhlawumbe kufanele uhlole izinhlobo ezihlukahlukene ezifana ne-Ostarine neLigandrol. Unolwazi oluningi nolucwaningo olutholakalayo.

Kuthiwa i-YK11 ingaba yingozi kulokhu. Ukukhuluma nge-hypothetically, kungathinta izinwele zokukhula, intambo yezwi, i-prostate impilo nezinye izitho ezibalulekile emzimbeni.


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Okubhekiselweyo nokuhlungwa komkhiqizo

I-YK-11 Isikhathi se-Cycle kanye ne-Experience Feedback kusuka kubasebenzisi bangempela

Okubhekwayo

  1. Thevis, M., Piper, T., Dib, J., Lagojda, A., Kühne, D., Packschies, L., ... & Schänzer, W. (2017). Ukuhlukaniswa kwe-mass spectrometric ye-androgen receptor receptor modulator (SARM) YK-11 ngezinhloso zokulawula ukudonswa. Ukuxhumana okusheshayo ku-Mass Spectrometry, 31(14), i-1175-1183.
  2. Kanno, Y., Ota, R., Someya, K., Kusakabe, T., Kato, K., & Inouye, Y. (2013). I-module ye-androgen receptor modulator ekhethiwe, i-YK11, ilawula umehluko we-myogenic wama-myoblasts we-C2C12 yi-follistatin. Bulletin yezinto eziphilayo kanye nezokwelapha, 36(9), i-1460-1465.
  3. Piper, T., Dib, J., Putz, M., Fusshöller, G., Pop, V., Lagojda, A., ... & Thevis, M. (2018). Izifundo ku-vivi metabolism ye-SARM Y1K11: Ukukhonjwa nokuhlukaniswa kwe-metabolites okungase kube usizo ekulawuleni i-doping. Ukuhlolwa kwezidakamizwa nokuhlaziywa, 10(11-12), i-1646-1656.

I-Shangke Chemical yinkampani ephezulu echwepheni ezisebenzayo ezizimele eziphambili zokwelapha (APIs). Ukuze ulawule ikhwalithi ngesikhathi sokukhiqiza, inqwaba yabachwepheshe abanolwazi, imishini yokukhiqiza yokuqala kanye nama-laboratories yiwona amaphuzu ayisihluthulelo.

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