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I-Raw Compound 7P powder (1890208-58-8)

I-Compound 7p powder yasungulwa njengelinye uchungechunge lwamakhemikhali ngenhloso yokukhomba i-thromboxane esebenzayo kabili .......


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum
Umthamo: 1145kg / inyanga

Incazelo

I-Raw Compound 7P powder (1890208-58-8) ividiyo

I-Raw Compound 7P powder (1890208-58-8) Incazelo

I-Raw Compound i-7P powder ekhuthaza ukuphuma kwe-neurite kwe-neurons eyinhloko ekhushulwa evela ku-hippocampus, i-cortex ye-cerebral, ne-retina. ekwenzeni imfuyo ye-optic nerve injection, i-Raw Compound 7P powder yaboniswa ukukhuthaza ukukhula kwe-axon-gnumx axx emihle, okubonisa ukuthi umsebenzi we-in vitro neurite we-Raw Compound 43P powder uhumusha ekuvuseleleni ukuvuselelwa kwe-axon ku-vivo. I-Raw Compound 7P powder kanye nokucaciswa kwezinqubo ezenza kube khona ukuvuselelwa kwe-axon e-vivo kuzohlinzeka ngesisekelo esihle semizamo yesikhathi esizayo yokuthuthukisa amasu ekwelashwa.

Raw I-2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide (i-Compound 7P) powder (1890208-58-8) Siziqu

Igama Product I-2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (i-4-methoxy-3-pyridinyl) i-acetamide (i-Raw Compound 7P powder)
Igama leKhemikhali I-2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (i-4-methoxy-3-pyridinyl) i-acetamide (i-Raw Compound 7P powder)
Brand NAme I-Raw Compound 7P powder
I-Drug Class Izidakamizwa zeNootropic
CAS Inombolo 1890208-58-8
InChIKey I-NAXWKPFXCOBXLE-UHFFFAOYSA-N
I-molecular Fi-ormula C22H23N3O5S
I-molecular Weziyisishiyagalombili 441.508g
IMisa ye-Monoisotopic 440g / mol
Iphuzu lokuxuba N / A
Fukuvuselela kabusha Pi-oint N / A
I-Half Half-Life N / A
Color powder emhlophe
Sukufaneleka kancane incibilika emanzini nase-ethanol.
Sukuhlushwa Tukushisa Gcina ekamelweni lokushisa, emgodini ovalwe, gwema ukushisa okuqinile nokukhanya.
Aukuphikisana • Ukwandisa ukuxhumana
• Ithuthukisa isimo sengqondo
• Kusiza ukulwa nokukhathala
• Ukuvimbela uketshezi ngaphakathi kwengqondo
• Ukuphatha umonakalo ohlotshiswe ngophuzo ophuzweni

Raw I-XLUMXP yekhamera powder (1890208-58-8) Incazelo

I-Raw Compound 7P (i-2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide) ekhuphula ukuphuma kwe-neurite kwe-neurons ephakeme ekhushulwa etholakala ku-hippocampus , i-cortex ye-cerebral, ne-retina. ekwenzeni imfuyo ye-optic nerve injection, i-Raw Compound 7P powder yaboniswa ukukhuthaza ukukhula kwe-axon-gnumx axx emihle, okubonisa ukuthi umsebenzi we-in vitro neurite we-Raw Compound 43P powder uhumusha ekuvuseleleni ukuvuselelwa kwe-axon ku-vivo. I-Raw Compound 7P powder kanye nokucaciswa kwezinqubo ezenza kube khona ukuvuselelwa kwe-axon e-vivo kuzohlinzeka ngesisekelo esihle semizamo yesikhathi esizayo yokuthuthukisa amasu ekwelashwa.

Ukusetshenziswa kwe-Compound 7P powder (1890208-58-8)

I-Compound 7p (2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide) ibonise umsebenzi ophakeme ngokumelene namangqamuzana omdlavuza wesibeletho. Emgodini ongenasici we-xenograft model owafakelwa ngama-HeLa cells, i-7p yabonisa ukuvinjelwa kwesilinganiso somthamo wokukhula kwesisu somlomo wesibeletho. Ukuhlolwa kwakhe kwezinto eziphathekayo ezithwala izicubu kuveza ukuthi i-7p ithuthukise i-microstructure ngendlela exhomeke emthamo. I-Compound 7p iphinde yandise inani lama-HeLa amaseli ku-G0 / G1 nesigaba se-S futhi yehlise kakhulu lokho kwesigaba se-G2 / M. Imiphumela ye-7p ku-C-caspase-3, C-caspase-9, Bcl-2 ne-Bax inkulumo ku-HeLa amaseli nayo yanqunywa.

I-tubulin polymerization test, ukuhlolwa kwe-immunofluorescence, ukuhlaziywa kwesigidi se-cell kanye nesimo sokuncintisana se-tubulin-binding kwafakazela ngokuqinile ukuthi i-7p iyi-colchicine yokubopha indawo yesimiso se-tubulin.

Izinzuzo of I-XLUMXP yekhamera powder (1890208-58-8)

Ukuvuselelwa okuhlanganisiwe kwe-7p kwe-optic echotshoziwe

Lungisa ikhanda lekhanda elilimazayo

Kunconywe I-XLUMXP yekhamera powder (1890208-58-8) Isilinganiso

I-Compound 7p ibonise i-100% ukuvimbela ama-parasitemia ngosuku 4 ngamanani amaningi (i-100, i-50, ne-25 mg / kg) enikeziwe ngezinsuku ezine ezilandelanayo, kodwa ku-100 mg / kg, zonke izigundane zisinda futhi zelashwa, kuyi-50 mg / kg, amagundane amathathu amahlanu asinda futhi amakhambi amabili aphulukiswa, futhi ku-25 mg / kg, akekho namagundane asinda


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I-Shangke Chemical yinkampani ephezulu echwepheni ezisebenzayo ezizimele eziphambili zokwelapha (APIs). Ukuze ulawule ikhwalithi ngesikhathi sokukhiqiza, inqwaba yabachwepheshe abanolwazi, imishini yokukhiqiza yokuqala kanye nama-laboratories yiwona amaphuzu ayisihluthulelo.

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