I-Nicotinamide riboside chloride (NR-CL) (23111-00-4)

Mashi 11, 2020
SKU: 129938-20-1
5.00 koku 5 ngokusekelwe ku 1 isilinganiso ikhasimende

I-Nicotinamide riboside (NR) iyi-nicotinamide adenine dinucleotide (NAD +) yevithamini eyandulelayo yamuva nje. I …….


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum

I-Nicotinamide riboside chloride (NR-CL) (23111-00-4) ividiyo

I-Nicotinamide riboside chloride (NR-CL) (23111-00-4) Siziqu

Igama Product I-Nicotinamide riboside chloride (NR-CL) (23111-00-4)
Igama leKhemikhali I-NRC; 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride; I-Nicotinamide ribose chloride; I-3-Carbamoyl-1- (β-D-ribofuranosyl) i-pyridinium chloride; I-3-carbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) i-pyridin-1-ium chloride; INicotinamide BD Riboside Chloride (WX900111); I-NR-CL;
CAS Inombolo 23111-00-4
InChIKey YABIFCKURFRPPO-IVOJBTPCSA-N
SMILE C1 = CC (= C [N +] (= C1) C2C (C (C (O2) CO) O) O) C (= O) N. [Cl-]
Formula Yamamolekhula C11H15ClN2O5
isisindo Yamamolekhula 290.7002
IMisa ye-Monoisotopic I-290.066949 g / mol
I-Melting Point N / A
Color white
Sithempeli le-torage -20 ° C I-Freezer
Isicelo izithasiselo zokudla, insimu yezemithi

Kuyini I-Nicotinamide riboside chloride(NR-CL)?

I-Nicotinamide riboside (NR) iyi-nicotinamide adenine dinucleotide (NAD +) yevithamini eyandulelayo yamuva nje. Uhlobo lwe-crystalline lwe-NR chloride lubizwa ngokuthi i-NIAGEN, okuyindlela yokwenza okwenziwe nge-nicotinamide riboside nomthombo lapho i-nicotinamide ngohlobo lwe-nicotinic acid ingatholakala khona nge-bioavaav futhi ibhekwa njengephephile (GRAS) ngokujwayelekile. I-NR chloride iyisihloko sezaziso ezimbili zokudla zokuthambisa, ezisetshenziswa ikakhulu kwizithasiselo zokudla.

INicotinamide Riboside Chloride isithako semvelo esitholakala obisini. Empeleni ihlobene neacon kanye nezinye izinhlobo ze-vithamini B3. Abanye abacwaningi bathole ukuthi iNicotinamide Riboside Chloride inezici ezithile ezihlukile ezingakhulisa imetabolism yomuntu ukusiza ukushisa amakhalori amaningi nokuvikela isisindo. Ngaphezu kokuncipha kwesisindo, kusiza futhi ukukhulisa ukusebenza kwemisipha, ukukhulisa ukusetshenziswa kwamandla, kanye nokunciphisa izingozi ezibangelwa ushukela.

Futhi, ucwaningo kubantu luye lwabonisa ukuthi bobabili i-Nicotinamide Riboside Chloride iphakamisa amazinga e-NAD +, asiza ukujabulisa izimo ezithile ezihlobene nobudala, noma ngabe maduze nje ukwazi ukuthi kuzophumelela kangakanani.

Izinzuzo I-Nicotinamide riboside chloride(NR-CL)

I-Nicotinamide riboside chloride iyindlela yokwenziwa ye-nicotinamide riboside, izinzuzo zayo / ukusebenza kuyafana ne-nicotinamide riboside. Ibamba iqhaza emzimbeni we-metabolism emzimbeni, ingasetjenziselwa ukuvikela i-pellagra noma esinye isifo se-niacin defence kanye nokwehlisa i-cholesterol ne-triglycerides egazini. Iphinde isetshenziselwe ukwehlisa ingozi yokuhlaselwa yisifo senhliziyo kubantu abane-cholesterol ephezulu abaye baba nokuhlaselwa yinhliziyo. Kwesinye isikhathi isetshenziselwa ukwelapha isifo se-coronary artery isifo (isifo sokuqina kwemithambo yegazi), ukuvikela ukuvikela ubuchopho kanye nesibindi (inhliziyo, isifo sikashukela, isifo se-Alzheimer's).

Ngaphandle kwalokho, i-Nicotinamide riboside chloride nayo inezinye izinzuzo kubantu:

  • Ukugaya kahle nokufakwa kwamaprotheni namafutha;
  • Siza ukuguqula i-troptophan ebalulekile ye-amino acid ibe yiacin;
  • Yehlisa ukugabha, futhi unciphise imiphumela yokuthatha imishanguzo ngenxa yomlomo owomile nobunzima bokuchama;
  • Khuthaza ukuhlangana kwe-nucleic acid futhi uvikele ukuguga kwezicubu nezitho zomzimba, ngaleyo ndlela kufezeke inhloso yokulibazisa ukuguga;
  • I-Slow nocturnal muscle spasm, ukukhubazeka kwe-spastic kanye ne-neuritis yezandla neyezinyawo;
  • Ukwelashwa kwe-hypometabolism ye -gengenic kanye nokuthuthukisa imetabolism;
  • Ukuvimbela kanye nokwelashwa kokuntuleka kwe-Vitamin B6;
  • Ukwelashwa kwe-carpal tun tun syndrome;
  • Isiza ukunciphisa umzimba futhi iqinise ukusebenza kwemisipha.
  • Thuthukisa ukumelana komzimba kumaseli womdlavuza
  • Vimbela ukulahleka kwezindlebe
  • Ingabe i-diuretic yemvelo.
  • Ukuthatha imithamo emikhulu kungakhulula umlutha wezidakamizwa futhi kube nomphumela omuhle wokudedelwa.
  • Ukwenza ngcono ukusebenza kwamaseli we-epidermal, kanye nemisebenzi yamanye amaseli emzimbeni womuntu, ukugcina isikhumba siqhakaza.

I-Nicotinamide riboside chloride(NR-CL) ukusetshenziswa

Ngoba i-Nicotinamide riboside chloride inezakhiwo zemithi ezuzisayo, imvamisa isetshenziswa ezongezelweni zokudla, umuthi nasensimini yokudla.

Izikhombo:

  • UConze D, uBrenner C, uKruger CL. Ezokuphepha kanye ne-Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in Clomical Clinical Agency Of Healthy Overweight Adult, Blindinamide Riboside Chloride). I-Sci Rep. 2019 Jul 5; 9 (1): 9772. doi: 10.1038 / s41598-019-46120-z. PMID: 31278280 PMCID: PMC6611812.
  • I-Bogan, KL, Brenner, C. (2008). "I-Nicotinic acid, i-nicotinamide, ne-nicotinamide riboside: ukuhlolwa kwamangqamuzana amavithamini e-NAD + ekudleni kwabantu". Annu. UMfu Nutr. 28: 115-130. doi: 10.1146 / annurev.nutr.28.061807.155443. PMID 18429699.
  • I-Chi Y, i-Sauve AA (Novemba 2013). “I-Nicotinamide riboside, isakhi somkhondo ezitholakala ekudleni, siyivithamini B3 elinemiphumela kumandla we-metabolism kanye ne-neuroprotection”. UCrr Opin Clin Nutr Metab Ukunakekelwa. 16 (6): 657-61. doi: 10.1097 / MCO.0b013e32836510c0. PMID 24071780.

UKUHLELWA KANYE Nesitatimende:

Le Material ithengiswa Ukusetshenziswa Kocwaningo Kuphela. Imibandela Yokuthengisa Faka isicelo. Hhayi Ukusetshenziswa Komuntu, noma Ezokwelapha, Izilwane, noma Ukusetshenziswa Kwasekhaya.