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I-NSI-189 Base powder (1270138-40-3)

I-NSI-189 base powder eyinhlanzi i-anti-depressant yokuhlola, engaba khona engaphenywa nguNeuralstem, Inc. ....


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum
Umthamo: 1460kg / inyanga

Incazelo

I-NSI-189 Base powder (i-1270138-40-3) ividiyo

I-NSI-189 Base powder (1270138-40-3) Incazelo

I-NSI-189 Base powder i-nootropic kanye ne-neurogenic yocwaningo yamakhemikhali etholakala ku-nicotinamide ne-pyrazine. Lokho kwakusuka ku-pyrazine ne-nicotinamide. Ucwaningo luye lwabonisa ukuthi luvuselela i-neurogenesis ye-hippocampus yabantu-etholakala nge-neural stem cells e-vivo nase-vitro. Kuzimbongolo ezindala ezinempilo, i-NSI-189 iboniswe ukwandisa ivolumu ye-hippocampal nge-20% nokubonakalisa okuphawulekayo kokuziphatha kumamodeli wokucindezeleka kwegundane, okusho emthonjeni ongayenza ukubhekana nokucindezeleka. I-hippocampus inesibopho sokuhamba kwendawo, kanye nokuhlanganiswa kolwazi kusuka kwimemori yesikhashana kuya kwimemori yesikhathi eside.

I-chemical entity ivuselela ukukhula okusha kwe-neuron ku-hippocampus, okuyingxenye yobuchopho okukholakala ukuthi ibambe iqhaza ezimweni ezifana nokucindezeleka kokucindezeleka ngemuva kokucindezeleka (PTSD), isifo se-Alzheimer, kanye nokucindezeleka okukhulu kwe-MDD.

I-NSI-189 Base powder (1270138-40-3) Siziqu

Igama Product I-NSI-189 Base powder
Igama leKhemikhali (4-benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone; UNII-YVE9U408ZL; YVE9U408ZL;
Brand NAme I-NSI-189 Base powder
I-Drug Class Inhibitors; I-Nootropic
CAS Inombolo 1270138-40-3
InChIKey I-DYTOQURYRYYNOR-UHFFFAOYSA-N
I-molecular Fi-ormula C22H30N4O
I-molecular Weziyisishiyagalombili I-366.509 g / mol
IMisa ye-Monoisotopic I-366.242 g / mol
I-Melting Point N / A
I-Half Half-Life I-17.4 - amahora we-20.5
Color White
Sukufaneleka I-10 mM ku-DMSO
Sukuhlushwa Tukushisa Indawo Emile Emile
I-NSI-189 Base powder Aukuphikisana Isetshenziselwa ukwelashwa kwesinye isimo kuhlanganise nokugula okuphazamisayo okulandelayo emva kokucindezeleka (PTSD), isifo se-Alzheimer kanye nezinkinga eziphathelene nengqondo yokudala.

Raw Isisekelo se-NSI-189 powder (1270138-40-3)

I-NSI-189 Base powder i-nootropic kanye ne-neurogenic yocwaningo yamakhemikhali etholakala ku-nicotinamide ne-pyrazine. Lokho kwakusuka ku-pyrazine ne-nicotinamide. Ucwaningo luye lwabonisa ukuthi luvuselela i-neurogenesis ye-hippocampus yabantu-etholakala nge-neural stem cells e-vivo nase-vitro. Kuzimbongolo ezindala ezinempilo, i-NSI-189 iboniswe ukwandisa ivolumu ye-hippocampal nge-20% nokubonakalisa okuphawulekayo kokuziphatha kumamodeli wokucindezeleka kwegundane, okusho emthonjeni ongayenza ukubhekana nokucindezeleka. I-hippocampus inesibopho sokuhamba kwendawo, kanye nokuhlanganiswa kolwazi kusuka kwimemori yesikhashana kuya kwimemori yesikhathi eside.

I-chemical entity ivuselela ukukhula okusha kwe-neuron ku-hippocampus, okuyingxenye yobuchopho okukholakala ukuthi ibambe iqhaza ezimweni ezifana nokucindezeleka kokucindezeleka ngemuva kokucindezeleka (PTSD), isifo se-Alzheimer, kanye nokucindezeleka okukhulu kwe-MDD.

Isisekelo se-NSI-189 powder (1270138-40-3) Inqubo yezenzo?

Indlela yokwenza isenzo se-NSI-189 ichazwa amandla ayo okugqugquzela isizukulwane se-neurons esisha ku-hippocampus, noma kunjalo, imvukuzane eqondile ayimanje.

Izinzuzo isisekelo se-NSI-189 powder (1270138-40-3)

  • Kwangathi Kungathuthukisa UkuCognition
  • Kwangathi Kungathuthukisa Ukucindezeleka
  • Ungase Usize Nge-Stroke
  • Kungasiza Ngesifo Sikashukela

Kunconywe Isisekelo se-NSI-189 powder (1270138-40-3) Isilinganiso

I-NSI-189 base powder inesiphelo esincane kakhulu kubantu futhi ukuvivinywa okuningi kuye kwaba yizilwane zezilwane.

Lokho kukhulunywa, isigaba se-1B esingahleliwe ngokuphindaphindiwe sokuhlolwa kwesilinganiso samaminithi sibike ukuthi ukuphathwa kwe-40 mg ukulinganiselwa kwe-NSI-189 kanye / ngosuku, i-40 mg kabili / ngosuku, ne-40 mg ezintathu / ngosuku ngezinsuku ezingu-28

Okuqhamuka uma udla imishanguzo of Isisekelo se-NSI-189 powder (1270138-40-3)

I-neuropathy yangaphakathi ye-peripheral (i-peripheral neuropathy yangaphandle)

Ukwandisa ukudla

Ukwandisa ukudla okuthandayo ushukela (izinyo elimnandi)

Ukukhathala / i-malaise

Bonisa ukubekezelelana

Izinhloko ze-post-exercise

Ukwehlisa isisusa

I-Fugue ithi lapho ingxoxo yami engaphakathi yayingekho khona


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I-Shangke Chemical yinkampani ephezulu echwepheni ezisebenzayo ezizimele eziphambili zokwelapha (APIs). Ukuze ulawule ikhwalithi ngesikhathi sokukhiqiza, inqwaba yabachwepheshe abanolwazi, imishini yokukhiqiza yokuqala kanye nama-laboratories yiwona amaphuzu ayisihluthulelo.

Xhumana nathi