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I-Navy Nicton (Monomucleotide) i-Nicotinamide Mononucleotide (1094-61-7)

I-Nicotinamide Mononucleotide (NMN) ewutshani obuningi obunqunywe ukukhula komzimba ......


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum
Umthamo: 1370kg / inyanga

Incazelo

Ividiyo enamandla e-Nicotinamide Mononucleotide (NMN) (i-1094-61-7) ividiyo

I-Raw Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Incazelo

Raw Nicotinamide Mononucleotide powder ( "NMN" futhi "β-NMN") iyinhlangano nucleotide ethathwe ribose futhi nicotinamide. Thanda riboside nicotinamide, NMN kuyinto esuselwe niacin, futhi abantu enzyme ukuthi angasebenzisa NMN ukukhiqiza nicotinamide adenine ihambisane dinucleotide (NADH).

Ngenxa yokuthi i-NADH iyinkampani ye-cofactor yezinqubo ngaphakathi kwe-mitochondria, ye-sirtuin, ne-PARP, i-NMN iye yafundwa ngezibonelo zezilwane njenge-agent engahlinzeki nge-neuroprotective ne-anti-aging agent. Izinkampani zokondla ezokudla ziye zathengisa ngenkani imikhiqizo ye-NMN efuna lezo zinzuzo, nakuba kungekho isifundo somtholampilo kubantu abashicilelwe okwamanje.

I-Raw Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Imininingwane

Igama Product Iphunga elimnyama likaNicotinamide Mononucleotide (NMN)
Igama leKhemikhali I-Beta-nicotinamide ribose monophosphate; I-Nicotinamide Mononucleotide powder emanzini; I-AC1Q6RVF; I-AC1L23AN; I-NMN (+); SCHEMBL6858129
Brand NAme Mirailabo
I-Drug Class Ukwengeza kokudla
CAS Inombolo 1094-61-7
InChIKey DAYLJWODMCOQEW-TURQNECASA-N
I-molecular Fi-ormula C11H15N2O8P
I-molecular Weziyisishiyagalombili 334.22
IMisa ye-Monoisotopic I-335.229 g / mol
Ukuxuba Pi-oint > 96 ° C
Fukuvuselela kabusha Pi-oint Ayikho idethi etholakalayo
I-Half Half-Life Ngakho-ke, njengoba kuboniswe kuFi. 3, i-nicotinamide yanyamalala egazini nge-half-life yamahora we-5.3, kanti ingxenye yokuphila ye-nicotinic acid yayingu-1.1 ihora.
Color I-white to off-white powder
Sukufaneleka I-Methanol (Kancane), Amanzi (Kancane)
Sukuhlushwa Tukushisa I-Hygroscopic, -20˚C Freezer, ngaphansi kwe-Inert Atmosphere
Aukuphikisana Ukuze udlale indima yokukhulisa impilo nokuphatha isifo sikashukela

I-Nicotinamide Mononucleotide ebomvu (I-NMN) powder (1094-61-7) Incazelo

I-Nicotinamide Mononucleotide powder ephezulu ("NMN" ne "β-NMN") iyinucleuclede etholakala ku-ribose ne-nicotinamide. Njenga-nicotinamide riboside, i-NMN yikhiqiza ye-niacin, futhi abantu bane-enzymes engasebenzisa i-NMN ukukhiqiza i-nicotinamide adenine dinucleotide (i-NADH).

Ucwaningo olusha luphakamisa ukuthi i-NMN ingabuyisa imetabolism yamaselula, futhi ibe nomthelela omkhulu wokuguga. Njengoba kwenzeka ngokwemvelo emzimbeni, i-NMN (β-Nicotinamide mononucleotide) ibalulekile ekuguqulweni kwezakhi zibe namandla. Ukwengeza i-NMN njengengxenye yohulumeni wakho wansuku zonke kunganikeza amandla okuvuselela amandla, ukuvikelwa ekugugeni, nokunciphisa ingozi yezinkinga zenhliziyo. I-NMN i-cofactor ekusebenzeni kabusha kwe-redox, inqubo ebalulekile ekusebenzeni komzimba ekubunjweni kwe-ATP i-molecule enikezela amandla ephezulu. I-NMN iqukethe i-Sirtuin ekhiqiza inhlanganisela ekhuthaza ukucacisa nokuphila isikhathi eside.

Ukusetshenziswa kweNicotinamide Mononucleotide (NMN) powder (1094-61-7)

  1. I-Nicotinamide mononucleotide emangqamuzaneni omuntu ibamba indima ebalulekile ekuzalweni kwamandla, ihilelekile ku-NAD ye-intracellular (i-nicotinamide adenine dinucleotide, i-cell energy conversion conversion coenzyme ebalulekile), isetshenziselwa ukuguga, ukuwa ushukela wegazi kanye neminye imikhiqizo yokunakekelwa kwempilo.
  2. I-Nicotinamide Mononucleotide iyinvithamini engenawo amanzi, Umkhiqizo uwu-powder omhlophe omswakama, onamafutha noma ongenamakha, onomuncu, enomuncu, ekhululekile emanzini noma ethanol, engancibilika ku-glycerin.
  3. I-Nicotinamide Mononucleotidepowderis kulula ukuyitholela ngomlomo, futhi ingasakazwa kabanzi emzimbeni, imetabolites engaphezu kwesibalo noma i-prototype ngokushesha ixoshe umchamo. I-Nicotinamide iyingxenye ye-coenzyme I ne-coenzyme II edlala indima ye-hydrogen ekulethwa kwe-oxidation engxenyeni yokuphefumula, ingakhuthaza izinqubo zokufakelwa kwe-biological and tissu metabolism, igcine izicubu ezivamile (ikakhulukazi isikhumba, indlela yokugaya umzimba kanye nesistimu yezinzwa) ubuqotho bunendima ebalulekile.

Ngaphezu kwalokho, i-nicotinamide inokuvimbela nokwelapha kwe-block block, umsebenzi we-node node kanye nama-arrhythmias wokuhlola okusheshayo, i-nicotinamide ingathuthukisa kakhulu izinga lokushaya kwenhliziyo ne-atrioventricular block ebangelwa i-verapamil.

Izinzuzo of Nicotinamide Mononucleotide (I-NMN) powder (1094-61-7)

  • I-NMN Ikhuthaza Amandla Okusebenzisa I-Metabolism - I-NAD + isiza ukudiliza ukudla okunjenge-ushukela emandleni.
  • Ikhuthaza Ubunono Bempilo Kanye Nomsebenzi Wezinhliziyo.
  • Ukulungisa i-DNA yokuguga-i-NAD + isetshenziselwa ukulungisa izimpande ze-DNA eziphukile.
  • I-SIRTUIN Umgqugquzeli - i-NAD + iyadingeka ukuze izakhi zethu zofuzo zesikhathi eside zisebenze.
  • I-NMN yi-COMPound esetshenziswa yi-Harvard Sosayensi ukuguqula ezinye izibonakaliso zezicubu eziguga emagundeni owaqala ukugijima ku-NAD.
  • Ukwelashwa kwe-NMN kuvimbela ukulimala kakhudlwana kobuchopho obushukumisayo
  • Ukwelashwa kwe-NMN kukhulula ukukhubazeka kwengqondo
  • I-Nicotinamide mononucleotide inqanda ukuvuselelwa kwe-JNK ukuguqula isifo se-Alzheimer
  • I-NMN ingabuyisa ukuqondiswa kwamakhompi ku-r model

I-Nicotinamide Mononucleotide enconyiwe (I-NMN) powder (1094-61-7) Isilinganiso

Isilinganiso esivunyelwe ngokujwayelekile se-Nicotinamide Mononucleotide powder noma ikuphi phakathi kwe-250 - 1500 mg ngosuku.

I-NMN ixhunyiwe ngokushesha kakhulu futhi ine-half-life-life, ngakho-ke ukugcina ama-NAD + aphakeme kakhulu usuku ngangokunokwenzeka kunconywa ukuthi uthathe i-capsule eyodwa ye-125 mg lapho evuka futhi enye ntambama uma uthatha i-250 mg ngosuku.

Okuqhamuka uma udla imishanguzo of Nicotinamide Mononucleotide (I-NMN) powder (1094-61-7)

Ngenkathi i-Nicotinamide mononucleotide (NMN) i-powder iyinzuzo engcono kakhulu futhi ucwaningo luqhubeka, izifundo eziqhutshwa kuze kube manje zibonise ukuthi ziphephile kakhulu futhi aziyona into enobuthi.

Imiphumela emibi ayidlame, kodwa ukuzwakalisa, ukuzondwa, ukujuluka, nokucabangela kubike kwezinye izimo.


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Okubhekiselweyo nokuhlungwa komkhiqizo

I-2019 Latest Anti-Aging Izidakamizwa: I-Nicotinamide Mononucleotide (i-NMN)

Okubhekwayo

  1. Izigayidi, KF, Yoshino, J., Yoshida, S., et al. (I-2016). Ukulawulwa Kwesikhathi Eside Kokuphela Kwe-Nicotinamide Mononucleotide Kunciphisa Ukuguga Kwemvelo Ehlanganiswa Nokwemvelo Kwezinsana. I-Cell Metabolism.
  2. UJoshino, J., Mills, KF, Imai, SI, noJoon, MJ (2011). I-Nicotinamide Mononucleotide, i-NAD + ephakathi, isebenzisa i-Pathophysiology ye-Diet- kanye ne-Diabetes Ekhulelwe Ngayo Emantwini. I-Cell Metabolism.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., noSadoshima, J. (2014). I-Nicotinamide Mononucleotide, isiPhakathi seNAD + Synthesis, ivikela Inhliziyo kusuka Ischemia nokuphinda kufakwe kabusha.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, noMorris, MJ (2016). Hlola kuya eNhloko Ukuqhathaniswa Ukwelashwa Kwesikhathi Esifishane Nesandulela seNAD + iNicotinamide Mononucleotide (NMN) kanye namaviki ayisithupha Wokuzivocavoca Emagundeni Ase-Obese Abesifazane.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., et al. (2019) I-Slc12a8 yi-Nicotinamide Mononucleotide Transporter. Uhlobo lweMetabolism.
  6. De Picciotto, NE, Mills, KF, Imai, S., Gano, LB, et al. (I-2016). I-Nicotinamide Mononucleotide iguqula ukukhubazeka kwe-Vascular nokucindezeleka okuxubile ngamagundane asegugile.
  7. Yao, Z., Gao, Z., Yang, W., noJia, P. (2017). I-Nicotinamide Mononucleotide ivimbela ukuvuselelwa kwe-JNK ukuguqula izifo ze-Alzheimer.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., et al. (I-2018). I-NAD + I-Supplementation ihlanganisa izici ze-Alzheimer Key kanye ne-DNA Impendulo yokulimala ku-AD entsha ye-Mouse Model ne-Introduced DNA Repair Repair.

I-Shangke Chemical yinkampani ephezulu echwepheni ezisebenzayo ezizimele eziphambili zokwelapha (APIs). Ukuze ulawule ikhwalithi ngesikhathi sokukhiqiza, inqwaba yabachwepheshe abanolwazi, imishini yokukhiqiza yokuqala kanye nama-laboratories yiwona amaphuzu ayisihluthulelo.

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