I-Urolithin B

April 8, 2021

I-Urolithin B inciphisa ukonakala kwamaprotheni futhi inciphisa imisipha hypertrophy. I-Urolithin B ivimbela ukusebenza kwe-aromatase, i-enzyme eguqula i-estrogen ne-testosterone.

Ividiyo ye-Urolithin B

 

Imininingwane yamakhemikhali ye- I-Urolithin B

Igama Product I-Urolithin B powder
Igama leKhemikhali 3-hydroxy-6H-benzo [c] chromen-6-one

3-hydroxybenzo [c] chromen-6-one

Uro-B

I-3-Hydroxyurolithin

CAS Inombolo 1139-83-9
InChIKey I-WXUQMTRHPNOXBV-UHFFFAOYSA-N
SMILE C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
Formula Yamamolekhula C13H8O3
isisindo Yamamolekhula I-212.2 g / mol
IMisa ye-Monoisotopic I-212.047344 g / mol
I-Melting Point 247 ° C
Color omhlophe kuya ku-beige powder
solubility I-DMSO: i-soluble5mg / mL, icacile (ifudunyezwe)
Sithempeli le-torage I-2-8 ° C
Isicelo I-Urolithin B isetshenzisiwe ekwakheni umzimba nasendaweni yokwengeza.

Izikhombo

[1] U-Lee G, et al. Izindlela zokulwa nokuvuvukala kanye ne-antioxidant ye-urolithin B ku-microglia esebenzayo. I-Phytomedicine. 2019 Mar 1; 55: 50-57. [2]. URodriguez J, et al. Urolithin B, isilawuli esisanda kukhonjwa semisipha yamathambo. Imisipha kaJ Cachexia Sarcopenia. 2017 Aug; 8 (4): 583-597.

[2] Izindlela zokulwa nokuvuvukala kanye ne-antioxidant ye-urolithin B ku-microglia esebenzayo. Lee G, Park JS, Lee EJ, Ahn JH, Kim HS.

[3] Urolithin B, isilawuli esisanda kukhonjwa semisipha yamathambo URodriguez J, Pierre N, Naslain D, Bontemps F, Ferreira D, Priem F, Deldicque L, Francaux M.

[4] I-Urolithin B, i-gut microbiota metabolite, ivikela ukulimala kwe-myocardial ischemia / reperfusion nge-p62 / Keap1 / Nrf2 indlela yokusayina. UZheng D, Liu Z, Zhou Y, Hou N, Yan W, Qin Y, Ye Q, Cheng X, Xiao Q , UBao Y, uLuo J, uWu X.