I-Meclofenoxate (Centrophenoxine) (51-68-3)

Mashi 11, 2020
SKU: 541-15-1

I-Meclofenoxate (Centrophenoxine), ethengiswe ngaphansi kwegama lomkhiqizo uLucidril, ingenye yakuqala futhi yafundwa kakhulu ………


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 25kg / Drum

I-Meclofenoxate (Centrophenoxine) (51-68-3) ividiyo

I-Meclofenoxate (Centrophenoxine) powder Siziqu

Igama Product I-Meclofenoxate (Centrophenoxine) (51-68-3)
Igama leKhemikhali I-Clophenoxate;
I-Meclophenoxate;
Clofenoxin;
I-Proseryl;
I-2- (dimethylamino) ethyl 2- (4-chlorophenoxy) acetate
Brand NAme N / A
I-Drug Class Ama-anti-Allergic Agents, ama-Antineoplastic Agents, i-Antiparasitic Age
CAS Inombolo 51-68-3
InChIKey XZTYGFHCIAKPGJ-UHFFFAOYSA-N
I-molecular Fi-ormula C12H16ClNO3
I-molecular Weziyisishiyagalombili I-257.71 g / mol
IMisa ye-Monoisotopic I-257.081871 g / mol
Iphuzu lokubilisa 345.941 ° C ku-760 mmHg
Fukuvuselela kabusha Pi-oint N / A
I-Half Half-Life 2-4 amahora
Color white
Sukufaneleka Ukuqina kwamanzi: 2.9 mg / mL
Sukuhlushwa Tukushisa -20 ° C
Aukuphikisana I-Centrophenoxine powder isebenzise i-nootropics izidakamizwa kanye nesengezo sokudla.

Ukubuka konke kwe-Meclofenoxate (Centrophenoxine)

I-Meclofenoxate (Centrophenoxine), ethengiswe ngaphansi kwegama lomkhiqizo uLucidril, ingesinye sezidakamizwa zakudala noma ezifundwa kakhulu ezithiwa "nootropics". Kuyinto i-nootropic eyaziwayo futhi ehlonishwayo esezifakazele iminyaka engaphezu kwemihlanu yokusetshenziswa nokuhlolwa okuqinile komtholampilo.

Kwaqalwa ngo-1959 ososayensi e-French National Science Science Center njengendlela yokwelapha isifo i-Alzheimer's, ukugeleza kwegazi okunganele ukuya ebuchosheni, ‍ kanye nokwehla kwengqondo okuhlobene nobudala, lesi sidakamizwa sisetshenziselwe ukwelapha ukuphazamiseka kwengqondo okuhlobene nobudala, kanye ne-Alzheimer's kanye ne-dementia. Isetshenziswa futhi ngabantu abaphilile ukuthuthukisa inkumbulo nomsebenzi wokuqonda nokuthuthukisa impilo yonke yobuchopho.

Ukucwaninga kukhombise i-centrophenoxine powder ukuthi ibe yisinamandla senkumbulo enamandla ne-anti-ukuguga i-ejenti.

E-Europe, kunqunyelwe ukwelashwa kokulahleka kwememori okuhlobene nobudala, kepha kutholakala ngaphezulu kwekhawundi njengesengezo sokudla e-US naseCanada, lapho isetshenziselwa kakhulu izindawo zayo zokuthuthukisa ukuqonda.

Yini iMeclofenoxate (Centrophenoxine)?

ICentrophenoxine isetshenziswe njengesengezo sokudliwayo samakhono ayo okukhulisa inkumbulo.

ICentrophenoxine iyinhlanganisela yamakhemikhali amabili:

I-Dimethyl-aminoethanol (DMAE), okuyinto yemvelo etholakala kokunye ukudla (inhlanzi, ukudla kwasolwandle) kanye namanani amancane ebuchosheni. Kungumthombo we-choline futhi kunemiphumela ekhuthaza ubuchopho.

I-Parachlorphenoxyacetic acid (pCPA), inguqulo yokwenziwa yama-hormone okukhula kwesitshalo abizwa nge- “auxins”.

I-DMAE yisakhi esiyinhloko esisebenzayo kulo muthi. I-DMAE ayiweli kahle isithiyo segazi-ingqondo. Kodwa-ke, ngaphakathi kwe-centrophenoxine, ingadlula emvinjelweni wegazi-lobuchopho futhi ingene ebuchosheni ngokuphumelelayo

Lapho isingenwe emzimbeni, ingxenye ye-centrophenoxine ihlehlela ku-DMAE ne-pCPA esibindini. I-DMAE iguqulwa iguqulwe i-choline, kuyilapho i-centrophenoxine esele ijikeleza wonke umzimba.

Izinzuzo zeMeclofenoxate (Centrophenoxine)

ICentrophenoxine ingasiza ekulweni nomdlavuza.

ICentrophenoxine ingasiza ngezimpawu zokuqina kwesisu.

ICentrophenoxine ithuthukisa inkumbulo nokufunda, ingathuthukisa inkumbulo ezigulini zokuwohloka komqondo.

I-Centrophenoxine ikhonjisiwe ukuthuthukisa ukwakheka, ukugcinwa, kanye nokubuyiselwa kwezinkumbulo. Ukwakhiwa kwememori kuyathuthuka lapho sinamazinga aphezulu we-acetylcholine. Njengoba kunikezwe iqiniso lokuthi i-Centrophenoxine ithuthukisa imisebenzi ehlukahlukene ye-cholinergic, enye yezinto ezikhiqizwa yi-choline, phakathi kwamanye ama-phospholipids ahlukile

Imisebenzi Ebonakalayo Ethuthukisiwe

ICentrophenoxine ingasetshenziswa njenge-DMAE prodrug futhi lokhu kubaluleke kakhulu, njengoba le molekyuli isebenza kahle kakhulu ekunciphiseni amanye ama-molecule ayingozi ngaphakathi kobuchopho okungadala ukuncipha okukhulu kwemisebenzi yokuqonda. Uma kususwe la mamolekyulu, abantu asebekhulile banganciphisa ukuguga kwabo futhi baguqule imiphumela emibi yokuguga.

ICentrophenoxine inezinto ezilwa nokuguga kanye ne-Neuroprotential

ICentrophenoxine ikhonjisiwe ukwandisa isikhathi sokuphila kwamagundane aze afike ku-50%.

ICentrophenoxine ithuthukisa iMood and Motivation, kungasiza ukudambisa ukukhathazeka.

Izifundo zezilwane ziphakamisa ukuthi i-centrophenoxine inomphumela wokulinganisa wokulwa nokukhathazeka.‍

I-Meclofenoxate (Centrophenoxine) i-metabolism

I-Centrophenoxine isebenza ikakhulukazi ngokuletha nokukhulisa izenzo ze-choline. I-Choline ingumanduleli we-acetylcholine, i-neurotransmitter ebalulekile futhi engenamkhawulo ehambisana ngokuqinile ne-cuitive acuity, plasticity, nememori. Akukacaci ukuthi empeleni i-centrophenoxine inyusa kanjani amazinga e-choline ne-acetylcholine, kepha kucatshangwa ukuthi kungenzeka ukuthi ivele yehluke ngokwemvelo i-choline noma iguqula i-phospholipid esetshenziswayo esetshenziselwa ukukhiqiza i-acetylcholine. Kungakhathaleki ukuthi iyiphi indlela, kungamandla e-cholinergic okwenza i-centrophenoxine ibe yi-nootropic enamandla amakhulu

Ngaphezu kokukhiqizwa kabusha kokukhiqizwa kwe-acetylcholine, i-centrophenoxine yaziwa nangokuthi inamandla e-neuro evusa umsebenzi wobuchopho ngokuthuthukisa ukumuncwa kwe-glucose nokwandisa ukuthathwa komoya. Ngokwenza kanjalo, i-centrophenoxine yenza ubuchopho busebenze kahle, ngaleyo ndlela ithuthukise ukugxila, ukugxila, kanye nokucaca kwemicabango, ukuqeda lokho okubizwa ngokuthi yinkungqondo yobuchopho. Njenge-antioxidant enamandla, ikhipha imisebe yamahhala, ikhipha ubuthi futhi ihlanganyele kulungiswa kwamangqamuzana alimele. Okokugcina, kubuyisela emuva ukuguga kwengqondo ngokunciphisa noma ngisho nokuqeda ukwakhiwa kwemikhiqizo yokulahla imfucumfucu ethathwa njengokuthi "iyabheda futhi idwengule imibala."

Meclofenoxate (Centrophenoxine) imiphumela emibi nokuphepha.

ICentrophenoxine ngokuvamile ibhekwa njengephephile futhi engenabuthi. Kusetshenziswe iminyaka engaba ngu-50 ngaphandle kwemiphumela emibi enkulu ebonakalayo.

Kuthiwa umuthi obekezelelekayo kubantu abaningi abadala abanempilo kanye ne-senile ehlushwa ukulahleka kwememori.

Kodwa-ke, abanye abasebenzisi baye babhekana nemiphumela emibi emincane nemincane, kufaka phakathi isicanucanu, ikhanda, izinkinga zesisu kanye nokungalali.‍

ICentrophenoxine ayelulekwa abesifazane abakhulelwe ngenxa yokuqukethwe kwe-DMAE.

I-Meclofenoxate (Centrophenoxine) umthamo we-powder

ICentrophenoxine iyatholakala ngaphezulu kwekhawunta kumakhompiyutha aqukethe ama-200 ukuya kwangama-300 mg lilinye. Izivivinyo zomtholampilo ezivivinya imiphumela ye-centrophenoxine kwimisebenzi yokuqonda isebenzise imithamo yansuku zonke ye

I-1,200 mg kubantu asebekhulile abanempilo kanye nemithamo efinyelela ku-2,000 XNUMX mg ezigulini zokwehla kwengqondo.

Ukubeka phansi

ICentrophenoxine ingumthombo omuhle kakhulu we-choline, ungayithola ezitokisini eziningi ze-nootropic - ezinye ezivame kakhulu yiNoopept neRacetams.

I-Centrophenoxine ne-Aniracetam Stack

Nasi isibonelo sesitaki se-centrophenoxine esifaka i-aniracetam ethandwa kakhulu ye-racetam yokuthuthukisa ukugcinwa kwememori, imizwa, ubuhlakani, ngenkathi kunciphisa ukukhathazeka.

1-2x ngosuku

250 mg Centrophenoxine

I-750 mg Aniracetam

ICentrophenoxine neNoopept Stack

Nasi isibonelo sesitaki se-centrophenoxine esineNoopept, lesi sitaki singathuthukisa inkumbulo nokufunda, ngenkathi sinikeza izakhiwo ze-neuroprotective.

1-2x ngosuku

250 mg Centrophenoxine

I-20 mg Noopept

Izikhombo:

  • Endima ye-intracellular physicochemistry ku-genitocative gene expression ngesikhathi sokuguga kanye nomphumela we-centrophenoxine. Isibuyekezo. I-Zs-Nagy I et al. U-Arch Gerontol Geriatr. (1989)
  • Umuthi we-Cholinergic we-antipsychotic-indased tysive dyskinesia. Tammenmaa-Aho I, Asher R, Soares-Weiser K, Bergman H. Cochrane Database Syst Rev. 2018 Mar 19
  • Umsebenzi we-Cytotoxic wama-alkylating agents lapho ukhona we-centrophenoxine kanye nemikhiqizo yawo ye-hydrolysis. Sladek NE. J Pharmacol Exp Ther. 1977 Dec
  • Amandla womsebenzi we-antitumor we-cyclophosphamide ngo-centrophenoxine. Kanzawa F, Hoshi A, Tsuda S, Kuretani K. Gan. 1972 Aug
  • I-Centrophenoxine: imiphumela ebuchosheni be-mammalian asebegugile. UNandy K et al. J Am Geriatr Soc. (1978)
  • Imiphumela ehlukile ye-meclofenoxate ekulahlekelweni kwememori asebekhulile. UMarcer D et al. Ukuguga. (1977)
  • I-Nootropics powder centrophenoxine (meclofenoxate) izinzuzo nezitaki