I-Beta-Lactoglobulin (9045-23-2)

I-Beta-Lactoglobulin (9045-23-2) ividiyo

I-Beta-Lactoglobulin (9045-23-2) Siziqu

Igama Product	Beta-Lactoglobulin
Igama leKhemikhali	I-β-Lactoglobulin (LG); I-BLG; β-Lg
Brand NAme	N / A
I-Drug Class	N / A
CAS Inombolo	9045-23-2
InChIKey	N / A
I-molecular Fi-ormula	N / A
I-molecular Weziyisishiyagalombili	18,300
IMisa ye-Monoisotopic	N / A
Iphuzu lokubilisa	N / A
Fukuvuselela kabusha Pi-oint	N / A
I-Half Half-Life	N / A
Color	powder emhlophe
Sukufaneleka	I-H2O: 10 mg / mL
Sukuhlushwa Tukushisa	I-2-8 ° C
Aukuphikisana	I-β-Lactoglobulin A isetshenziswe ubisi lwe-bovine: • njengesibalo sokulinganiswa kocingo lwe-TriWave • njengezinga ekuboneni nasekuchazweni kwe-β-lactoglobulin kubisi lwe-bovine ngokubuyisela emuva isigaba esigabeni se-chromatography (HPLC) • ekuhlanzweni kanye nokulinganiselwa kwesisindo samaseli wamasampula e-proteinase I-β-Lactoglobulin isetshenzisiwe ekuboneni ukuhlukahluka kofuzo kwe-κ-kesiin ebisini ngobisi olugxile kwe-eleelectric egxile electrophoresis.

Ukubuka konke kweBeta-Lactoglobulin (9045-23-2)

I-β-Lactoglobulin yiprotheni enkulu ye-Whey yobisi lwenkomo nelezimvu (~ 3 g / l), futhi ikhona kwezinye izinhlobo eziningi zezilwane ezincelisayo; umehluko ophawuleka ngokuba ngabantu. Cishe ama-20% amaprotheni obisi lwe-bovine amaprotheni e-Whey, kanti ingxenye eyinhloko yi-beta-lactoglobulin. I-β-Lactoglobulin imvamisa isithako esiyinhloko kuma-powders e-Whey-based protein.

Amaphrotheni ama-Whey angaba yingozi yokudla ekudla. Ubisi lweBovine lungenye yezithako ezibaluleke kakhulu zokudla kwe-allergenic, ikakhulukazi ezinganeni. Ngenxa yalokho, ukubhalwa kwe-beta-lactoglobulin noma ubisi kuyimpoqo emazweni amaningi. Noma kungekho mkhawulo osemthethweni wamaprotheni e-Whey, kunconyelwa kakhulu ukuthi abakhiqizi bokudla bavivinye ukugxila okuncane kakhulu ukuvikela abantu abangazweli futhi bagweme ukukhumbula okuhlobene ne-allergen.

Kuyini Beta-Lactoglobulin ?

I-Beta-Lactoglobulin (ß-lactoglobulin, BLG) yiprotheni enkulu ye-Whey kubisi oluvuthayo futhi ikhona ubisi lwezinye izilwane. Cishe ama-20% amaprotheni obisi lwe-bovine amaprotheni e-Whey, kanti ingxenye eyinhloko yi-beta-lactoglobulin. I-Beta-Lactoglobulin imvamisa isithako esiyinhloko kuma-powders e-Whey-based protein.

IBeta-lactoglobulin iprotheni yomhlaba wonke yomndeni we-lipocalin. Inesisindo samangqamuzana ayi-18,300 futhi inezinsalela eziyi-162 zama-amino acid, kufaka phakathi inani eliphakeme lama-amino acid (ama-BCAAs).

I-Beta-lactoglobulin (b-lactoglobulin / BLG) ingenye yama-allergens amakhulu obisini lwenkomo. Ingenye yamaprotheni ajwayelekile obisini ukudala ukungafani komzimba, yize abantu abaningi ngokuvamile bengazwani namaprotheni obisi angaphezu koyedwa. I-BlG yiprotheni eliningi kunawo wonke e-Whey, ibalwa ngamaphesenti ama-50 amaprotheni ephelele engxenyeni ye-lactoserum futhi cishe amaphesenti ayishumi obisi lwenkomo.

Ngokuvamile, ama-globulin ngamaprotheni amancane ahlanganisa ukwakheka okuphelele, futhi ama-lactoglobulin angama-globulins akhona obisini. Lapho i-casein ikhishwa ubisi (ngokwesibonelo, nge-rennet noma nge-acidity), ama-lactoglobulins asala ngemuva e-Whey (kanye ne-lactalbumin, i-lactose, amaminerali nama-immunoglobulins). Amaprotheyini acishe abe yi-10% yamakhompiyutha omile we-Whey, kanti i-beta-lactoglobulin icishe ibe yi-65% yalawo 10%.

I-Alpha-lactoglobulin ibandakanyeka ekuqakanisekeni kwe-lactose. Inhloso ye-beta-lactoglobulin ayicaci kahle, futhi yize ingabopha ama-molecule amaningi amancane e-hydrophobic, inhloso enkulu kungaba nje ukwenza njengomthombo wama-amino acid. I-Beta-lactoglobulin nayo ikhonjisiwe ukuthi ikwazi ukubopha i-iron nge-siderophores ngakho-ke ingahle ibambe iqhaza ekulweni namagciwane.

‍

Izinzuzo zeBeta-Lactoglobulin

Ukubhekana neqiniso lokuthi i-Whey protein ingxube ye-beta-lactoglobulin, i-alpha lactalbumin, i-bovine serum albhamuin nama-immunoglobins. Abantu bavame ukusebenzisa i-Whey njengesengezo, eceleni kokuzivocavoca umzimba, ukusiza ukuthuthukisa ukwakheka kwamaprotheni emisipha nokukhuthaza ukukhula kwesisindo semisipha esindayo.

Izinzuzo ezingaba khona zifaka phakathi ukusiza ukuncipha kwesisindo, izindawo ezilwa nomdlavuza, i-cholesterol ephansi, i-asthma, umfutho wegazi kanye nesifo senhliziyo, ukunciphisa ukwehla kwesisindo kubantu abane-HIV.

Ngokungafani nelinye iprotheni le-Whey eliyinhloko, i-α-lactalbumin, awukho umsebenzi ocacile okhonjwe i-β-lactoglobulin, lokhu yize kuyingxenye enkulu yokwakheka kwamaprotheni asemhlabeni wonke ahlukaniswe ne-Whey (β-lactoglobulin ≈⁠i65%, I-cy-lactalbumin ≈⁠⁠i25%, i-serum albhamuin ≈⁠⁠i8, amanye ≈⁠i2%). I-β-lactoglobulin yiprotheyini ye-lipocalin, futhi ingabopha ama-molecule amaningi we-hydrophobic, iphakamisa iqhaza endabeni yokuhamba kwabo. I-β-lactoglobulin nayo ikhonjisiwe ukuthi ikwazi ukubopha i-iron nge-siderophores futhi ngaleyo ndlela ibambe iqhaza ekulweni namagciwane. I-Homologue ye-β-lactoglobulin iyantula ubisi lwebele lomuntu.

IBeta-Lactoglobulin (BLG) yiprotheyini elinamafutha amaningi kunobisi lwe-bovine. I-LG ifundwe kabanzi embonini yokudla ngenxa yemiphumela yayo yokudla okungenamsoco nokusebenza kwezinqubo ezahlukahlukene zokuphilayo.

Ngokwengeziwe, i-BLG ingaba yisakhi eshibhile se-antioxidant esitholakala kalula futhi esisheshe sitholakale. I-BlG kungenzeka ukuthi isebenze njengesakhi se-antioxidant esitholakala kalula futhi eshibhile empilweni yansuku zonke. Umbiko wethu owedlule ukhombisile ukuthi i-cysteine ​​yamahhala ye-BLG idlala indima yokuvikela esimweni sobisi lwe-antioxidant. I-BLG ibhekele u-50% womsebenzi wobisi we-antioxidant. Hhayi kuphela ukuthi i-BLG ingasebenza ngokuqondile njengesakhi se-antioxidant, ingathwala namanye ama-antioxidants ngephakethe lakhe elibophayo le-ligand. Ngakho-ke, ikhulisa kokubili bioavailability nenani lama-antioxidants atholakalayo.

I-β-Lactoglobulin yiprotheni enkulu ye-Whey ebisi ebusheni ebalwe cishe amaphesenti ama-50 amaprotheni ku-Whey kodwa ayitholakali ebisini lomuntu. I-β-Lactoglobulin ibeka izici ezahlukahlukene ezisebenzayo nezondlayo ezenze ukuthi le protein ibe yinto ehambelana nezinto eziningi zokudla kanye nokusebenzisa okuningi kwe-biochemical.

Imiphumela emibi yeBeta-Lactoglobulin

I-Beta-lactoglobulin (b-lactoglobulin / BLG) ingenye yama-allergens amakhulu obisini lwenkomo. Ingenye yamaprotheni ajwayelekile obisini ukudala ukungafani komzimba, yize abantu abaningi ngokuvamile bengazwani namaprotheni obisi angaphezu koyedwa. I-BlG yiprotheni eliningi kunawo wonke e-Whey, ibalwa ngamaphesenti ama-50 amaprotheni ephelele engxenyeni ye-lactoserum futhi cishe amaphesenti ayishumi obisi lwenkomo.

Izimpawu zokuphendula kwe-beta-lactoglobulin kungaba:

Ubomvu noma isifuba

Itching

I-nausea

Ukuvimbela

Ukukhathazeka kwesisu

Uhudo

Ukuvuvuka

ukuqunjelwa

Anaphylaxis (akuvamile)

I-Beta-Lactoglobulin powder kusebenzisa

I-β-Lactoglobulin yiprotheni enkulu ye-Whey ebisi ebusheni ebalwe cishe amaphesenti ama-50 amaprotheni ku-Whey kodwa ayitholakali ebisini lomuntu. I-β-Lactoglobulin ibeka izici ezahlukahlukene ezisebenzayo nezondlayo ezenze ukuthi le protein ibe yinto ehambelana nezinto eziningi zokudla kanye nokusebenzisa okuningi kwe-biochemical.

Izikhombo:

Ama-β-Lactoglobulin afaka amandla okushisa njengabathwali bamafutha e-polyunsaturated. I-Perez AA, Andermatten RB, Rubiolo AC, Santiago LG Food Chem. 2014 Sep 1; 158 (): 66-72.

Ukuhlolwa kwesakhiwo nokuhlolwa kwe-allergenicity kwe-bovine β-lactoglobulin okuphathwa yi-sonication-assisted irradiation. Yang F, Zou L, Wu Y, Wu Z, Yang A, Chen H, Li X. J Dairy Sci. 2020 Feb 26

Ukuhlaziywa kweGenomic of Milk Amaprotein Izingcezu eBrown Swiss Cattle. IMarto Mota LF, Pegolo S, Bisutti V, Bittante G, Cecchinato A. Izilwane (Basel). 2020 Feb 2

---