I-Beta-Lactoglobulin (9045-23-2)

I-Beta-Lactoglobulin (9045-23-2) ividiyo

I-Beta-Lactoglobulin (9045-23-2) Siziqu

Igama Product	Beta-Lactoglobulin
Igama leKhemikhali	β -I-Lactoglobulin (i-LG); BLG; β -Lg
Brand NAme	N / A
I-Drug Class	N / A
CAS Inombolo	9045-23-2
InChIKey	N / A
I-molecular Fi-ormula	N / A
I-molecular Weziyisishiyagalombili	18,300
IMisa ye-Monoisotopic	N / A
Iphuzu lokubilisa	N / A
Fukuvuselela kabusha Pi-oint	N / A
I-Half Half-Life	N / A
Color	powder emhlophe
Sukufaneleka	I-H2O: 10 mg / mL
Sukuhlushwa Tukushisa	I-2-8 ° C
Aukuphikisana	I-β-Lactoglobulin A isetshenziswe ubisi lwe-bovine: • njengesibalo sokulinganiswa kocingo lwe-TriWave • njengezinga ekuboneni nasekuchazweni kwe-β-lactoglobulin kubisi lwe-bovine ngokubuyisela emuva isigaba esigabeni se-chromatography (HPLC) • ekuhlanzweni kanye nokulinganiselwa kwesisindo samaseli wamasampula e-proteinase I-β-Lactoglobulin isetshenzisiwe ekuboneni ukuhlukahluka kofuzo kwe-κ-kesiin ebisini ngobisi olugxile kwe-eleelectric egxile electrophoresis.

 

Ukubuka konke kweBeta-Lactoglobulin (9045-23-2)

I-act-Lactoglobulin yiprotheni enkulu yama-Whey obisi lwenkomo nolwezimvu (~ 3 g / l), futhi ikhona nakwezinye izinhlobo eziningi zezilwane ezincelisayo; okuhlukile okuphawulekayo ngabantu. Cishe ama-20% wamaprotheni obisi lwezinkomo angama-protein angama-whey, ingxenye yawo eyinhloko yi-beta-lactoglobulin. I-act-Lactoglobulin imvamisa iyisithako esiyinhloko kuma-whey-based protein powders.

Amaphrotheni ama-Whey angaba yingozi yokudla ekudla. Ubisi lweBovine lungenye yezithako ezibaluleke kakhulu zokudla kwe-allergenic, ikakhulukazi ezinganeni. Ngenxa yalokho, ukubhalwa kwe-beta-lactoglobulin noma ubisi kuyimpoqo emazweni amaningi. Noma kungekho mkhawulo osemthethweni wamaprotheni e-Whey, kunconyelwa kakhulu ukuthi abakhiqizi bokudla bavivinye ukugxila okuncane kakhulu ukuvikela abantu abangazweli futhi bagweme ukukhumbula okuhlobene ne-allergen.

Kuyini Beta-Lactoglobulin ?

I-Beta-Lactoglobulin (ß-lactoglobulin, BLG) yiprotheni enkulu ye-Whey kubisi oluvuthayo futhi ikhona ubisi lwezinye izilwane. Cishe ama-20% amaprotheni obisi lwe-bovine amaprotheni e-Whey, kanti ingxenye eyinhloko yi-beta-lactoglobulin. I-Beta-Lactoglobulin imvamisa isithako esiyinhloko kuma-powders e-Whey-based protein.

I-Beta-lactoglobulin yiprotheni yeglobular yomndeni we-lipocalin. Inesisindo samangqamuzana esingu-18,300 futhi inezinsalela ze-amino acid eziyi-162, kufaka phakathi inani eliphakeme kakhulu lama-amino acid (BCAAs).

I-Beta-lactoglobulin (b-lactoglobulin / BLG) ingenye yama-allergens amakhulu obisini lwenkomo. Ingenye yamaprotheni ajwayelekile obisini ukudala ukungafani komzimba, yize abantu abaningi ngokuvamile bengazwani namaprotheni obisi angaphezu koyedwa. I-BlG yiprotheni eliningi kunawo wonke e-Whey, ibalwa ngamaphesenti ama-50 amaprotheni ephelele engxenyeni ye-lactoserum futhi cishe amaphesenti ayishumi obisi lwenkomo.

Ngokuvamile, ama-globulin ngamaprotheni amancane ahlanganisa ukwakheka okuphelele, futhi ama-lactoglobulin angama-globulins akhona obisini. Lapho i-casein ikhishwa ubisi (ngokwesibonelo, nge-rennet noma nge-acidity), ama-lactoglobulins asala ngemuva e-Whey (kanye ne-lactalbumin, i-lactose, amaminerali nama-immunoglobulins). Amaprotheyini acishe abe yi-10% yamakhompiyutha omile we-Whey, kanti i-beta-lactoglobulin icishe ibe yi-65% yalawo 10%.

I-Alpha-lactoglobulin ibandakanyeka ekuqakanisekeni kwe-lactose. Inhloso ye-beta-lactoglobulin ayicaci kahle, futhi yize ingabopha ama-molecule amaningi amancane e-hydrophobic, inhloso enkulu kungaba nje ukwenza njengomthombo wama-amino acid. I-Beta-lactoglobulin nayo ikhonjisiwe ukuthi ikwazi ukubopha i-iron nge-siderophores ngakho-ke ingahle ibambe iqhaza ekulweni namagciwane.

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Izinzuzo zeBeta-Lactoglobulin

Ukubhekana neqiniso lokuthi iprotheni le-Whey liyinhlanganisela ye-beta-lactoglobulin, i-alpha lactalbumin, i-bovine serum albumin, nama-immunoglobin. Abantu bavame ukusebenzisa i-whey njenge-supplementation, eceleni kokuzivocavoca umzimba, ukusiza ukuthuthukisa amaprotheni synthesis synthesis nokukhuthaza ukukhula kwesisindo somzimba esinciphile.

Izinzuzo ezingaba khona zifaka phakathi ukusiza ukuncipha kwesisindo, izindawo ezilwa nomdlavuza, i-cholesterol ephansi, i-asthma, umfutho wegazi kanye nesifo senhliziyo, ukunciphisa ukwehla kwesisindo kubantu abane-HIV.

Ngokungafani namanye amaprotheni amakhulu we-whey, i-α-lactalbumin, awukho umsebenzi ocacile okhonjelwe i-β-lactoglobulin, lokhu yize kuyingxenye enkulu yokwakheka kwamaqunga amaprotheni e-globular ahlukaniswe ne-whey (β-lactoglobulin ≈⁠ ⁠65%, I-α-lactalbumin ≈⁠⁠ 25%, i-serum albumin ≈⁠⁠8%, enye i-≈⁠2%). I-lact-lactoglobulin yiprotheni ye-lipocalin, futhi ingabopha ama-molecule amaningi we-hydrophobic, iphakamisa indima ekuthuthweni kwabo. I-lact-lactoglobulin nayo ikhonjisiwe ukuthi iyakwazi ukubopha i-iron ngokusebenzisa ama-siderophores futhi ngaleyo ndlela ingaba nendima ekulweni namagciwane. I-homologue ye-β-lactoglobulin ayinalo ubisi lwebele lomuntu.

IBeta-Lactoglobulin (BLG) yiprotheyini elinamafutha amaningi kunobisi lwe-bovine. I-LG ifundwe kabanzi embonini yokudla ngenxa yemiphumela yayo yokudla okungenamsoco nokusebenza kwezinqubo ezahlukahlukene zokuphilayo.

Ngokwengeziwe, i-BLG ingaba yisakhi esingabizi kakhulu se-antioxidant esifinyeleleka kalula futhi kalula. I-BLG ingahle isebenze njengesakhi sokulwa ne-antioxidant esifinyeleleka kalula futhi eshibhile empilweni yansuku zonke. Umbiko wethu wangaphambilini ukhombisile ukuthi i-cysteine ​​yamahhala ye-BLG idlala indima yokuvikela emvelweni we-antioxidant wobisi. I-BLG ibhekele u-50% womsebenzi wobisi we-antioxidant. Akukona nje ukuthi i-BLG isebenze ngokuqondile njengesakhi sokulwa ne-antioxidant, futhi ingathwala amanye ama-antioxidants ngephakethe layo elibopha i-ligand. Ngakho-ke, kwandisa kokubili ukutholakala kanye nenani lama-antioxidants atholakalayo.

I-β-Lactoglobulin yiprotheni enkulu ye-Whey ebisi ebusheni ebalwe cishe amaphesenti ama-50 amaprotheni ku-Whey kodwa ayitholakali ebisini lomuntu. I-β-Lactoglobulin ibeka izici ezahlukahlukene ezisebenzayo nezondlayo ezenze ukuthi le protein ibe yinto ehambelana nezinto eziningi zokudla kanye nokusebenzisa okuningi kwe-biochemical.

 

Imiphumela emibi yeBeta-Lactoglobulin

I-Beta-lactoglobulin (b-lactoglobulin / BLG) ingenye yama-allergens amakhulu obisini lwenkomo. Ingenye yamaprotheni ajwayelekile obisini ukudala ukungafani komzimba, yize abantu abaningi ngokuvamile bengazwani namaprotheni obisi angaphezu koyedwa. I-BlG yiprotheni eliningi kunawo wonke e-Whey, ibalwa ngamaphesenti ama-50 amaprotheni ephelele engxenyeni ye-lactoserum futhi cishe amaphesenti ayishumi obisi lwenkomo.

Izimpawu zokuphendula kwe-beta-lactoglobulin kungaba:

Ubomvu noma isifuba

Itching

I-nausea

Ukuvimbela

Ukukhathazeka kwesisu

Uhudo

Ukuvuvuka

ukuqunjelwa

Anaphylaxis (akuvamile)

 

I-Beta-Lactoglobulin powder kusebenzisa

I-β-Lactoglobulin yiprotheni enkulu ye-Whey ebisi ebusheni ebalwe cishe amaphesenti ama-50 amaprotheni ku-Whey kodwa ayitholakali ebisini lomuntu. I-β-Lactoglobulin ibeka izici ezahlukahlukene ezisebenzayo nezondlayo ezenze ukuthi le protein ibe yinto ehambelana nezinto eziningi zokudla kanye nokusebenzisa okuningi kwe-biochemical.

 

Izikhombo:

Ama-β-Lactoglobulin afaka amandla okushisa njengabathwali bamafutha e-polyunsaturated. I-Perez AA, Andermatten RB, Rubiolo AC, Santiago LG Food Chem. 2014 Sep 1; 158 (): 66-72.

Ukuhlolwa kwesakhiwo kanye ne-allergenicity yezinkomo β-lactoglobulin ephathwe yi-sonication-assisted irradiation. Yang F, Zou L, Wu Y, Wu Z, Yang A, Chen H, Li X. J Dairy Sci. 2020 Februwari 26

Ukuhlaziywa kweGenomic of Milk Amaprotein Izingcezu eBrown Swiss Cattle. IMarto Mota LF, Pegolo S, Bisutti V, Bittante G, Cecchinato A. Izilwane (Basel). 2020 Feb 2

 

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