I-Lactoferrin (146897-68-9)

I-Lactoferrin (146897-68-9) ividiyo

Lactoferrin powder Siziqu

Igama Product	Lactoferrin
Igama leKhemikhali	i-lactotransferrin (LTF)
Brand NAme	N / A
I-Drug Class	N / A
CAS Inombolo	146897-68-9
InChIKey	N / A
I-molecular Fi-ormula	C141H224N46O29S3
I-molecular Weziyisishiyagalombili	I-87 kDa
IMisa ye-Monoisotopic	N / A
Iphuzu lokubilisa	N / A
Fukuvuselela kabusha Pi-oint	N / A
I-Half Half-Life	N / A
Color	pink
Sukufaneleka	I-H2O: 1 mg / mL
Sukuhlushwa Tukushisa	I-2-8 ° C
Aukuphikisana	N / A

 

Kuyini Lactoferrin?

I-Lactoferrin (LF), eyaziwa nangokuthi lactotransferrin (LTF), yi-glycoprotein emelelwa kakhulu emanzini ahlukahlukene emibhalo kubandakanya ubisi. Le CRM yobude obugcwele ilungile njengokuqala kokusetjenziselwa ukusebenzisa ama-calibrators noma izilawuli zezinhlobo ezahlukahlukene zokuhlola izinhlelo ze-LC-MS / MS kufaka phakathi ukuhlolwa kwe-allergen, ukuhlolwa kwefomula yezinsana, uhlelo lokudla noma lokudla okunempilo nokunempilo

I-Colostrum, ubisi lokuqala olukhiqizwa ngemuva kokuba ingane luzelwe, luqukethe amazinga aphezulu e-lactoferrin, okuyisikhathi esiphindwe kasikhombisa inani elitholwa ubisi olukhiqizwa kamuva. I-Lactoferrin nayo itholakala uketshezi esweni, ekhaleni, emgudwini wokuphefumula, amathumbu, kwenye indawo. Abantu basebenzisa i-lactoferrin njengomuthi.

I-Lactoferrin isetshenziselwa ukwelapha izilonda zesisu namathumbu, uhudo kanye ne-hepatitis C. Iyasetshenziswa njenge-antioxidant futhi ivikele ekuthelelekeni kwamagciwane kanye namagciwane. Okunye ukusetshenziswa kufaka phakathi ukuvuselela amasosha omzimba, ukuvimbela ukulimala kwezicubu okuhlobene nokuguga, ukukhuthaza amagciwane anamathumbu anempilo, ukuvimbela umdlavuza, nokulawula indlela umzimba owucubungula ngayo i-iron.

Abanye abacwaningi baphakamisa ukuthi i-lactoferrin ingahle ibambe iqhaza ekuxazululeni izinkinga zezempilo zomhlaba njengokushoda kwensimbi kanye nohudo olunzima.

Kwezolimo zezimboni, i-lactoferrin isetshenziselwa ukubulala amabhaktheriya ngesikhathi sokufakwa kwenyama.

I-Lactoferrin iyingxenye yamasosha omzimba futhi inomsebenzi we-antimicrobial. Ngaphezu kwemisebenzi esemqoka yokuhlanganisa nokuthutha insimbi, iLactoferrin nayo inemisebenzi nezimfanelo zensimbi elwa namagciwane, i-antivirus, ukumelana nezimuncagazi, i-catalysis, ukuvimbela umdlavuza nokulwa nomdlavuza, ukungezwani komzimba nokuvikelwa kwemisebe. Abanye abantu bathatha i-lactoferrin Izithako ukuze uthole izinzuzo zokulwa nokuvuvukala kanye ne-antioxidant.

Izinzuzo zeLactoferrin

Imiphumela Yokulwa Nezifo

Yize umshini oqondile ungakasungulwa okwamanje, i-lactoferrin iyinto eyaziwayo yokulwa nokuvuvukala kubantu.

I-Lactoferrin ku-amniotic fluid yinto ebalulekile yokunciphisa ukuvuvukala kwengane kwabesifazane abakhulelwe ngokunciphisa amazinga e-IL-6 futhi kunciphise ukutheleleka okubangela ukuvuvukala.

Inezinto ezilwa nokuvuvukala lapho zisebenzelana namasosha omzimba ngokumelene ne-Epstein-Barr virus, inciphisa ukuvuvukala ngokuvimbela ukuvulwa kwe-TLR2 ne-TLR9 kwi-virus ye-DNA.

Izakhiwo ze-antibacterial

I-Lactoferrin isiza ukumisa umsebenzi wamagciwane. Iningi lamagciwane lidinga i-iron ukuze lisebenze, futhi i-lactoferrin ingavimba amabhaktheriya ukuthi athathe i-iron emzimbeni womuntu.

Ngaphezu kwalokhu, kungavimba i-carbohydrate metabolism metabolism, kuqinise izindonga zamaseli abo, noma kuhlanganyele nama-lysozymes obisini ukumisa amagciwane.

Iqhaza ekukhuleni kwengane / kwezinsana

Izinsana zidinga i-lactoferrin ukuthuthukisa nokuzivumelanisa nesistimu yamathumbu. Inesibopho sokuhlukanisa amaseli amancane wamathumbu we-epithelial, ethinta isisindo esincane samathumbu, ubude, kanye ne-enzyme expression.

Ezithweni zomuntu, i-lactoferrin isebenza njengomlawuli wokukhula kwethambo ezigabeni zokuqala zokukhula kwamathambo omuntu.

I-Lactoferrin ikhuthaza ukukhula kwezicubu ze-cartilaginous ezigabeni ezahlukahlukene zokukhula kwe-fetus ngokuvuselela ama-osteocytes angakafiki kanye nama-osteoblasts.

Ezithweni zomuntu, i-Lactoferrin ikhuthaza ukumuncwa kwe-iron kanye nokuthuthukiswa komngcele wamabhulashi, okuvumela ukukhula okunempilo nokukhula kwezisu ngaphambi kokuzalwa.

Amazinga aphezulu we-Lactoferrin esibelethweni avimbela ukutheleleka kanye nokuqhekeka kwezilungu zamalungu e-fetus ngenkathi ekhulisa ukukhululeka kokubeletha.

 

Ngabe uLactoferrin usebenza kanjani?

I-Lactoferrin isiza ukulawula ukufakwa kwe-iron emathunjini kanye nokulethwa kwensimbi kumaseli.

Kubonakala futhi kuvikela ekuthelelekeni ngegciwane, mhlawumbe ngokuvikela ukukhula kwamagciwane ngokuphuca izakhi ezibalulekile noma ngokubulala amagciwane ngokubhubhisa izindonga zeseli yazo. I-lactoferrin equkethwe obisini lukamama kuthiwa isiza ekuvikeleni izinsana ezincelisa ibele ezifweni zamagciwane.

Ngaphezu kwezifo ezibangelwa amagciwane, i-lactoferrin ibonakala isebenza ngokulwa nezifo ezibangelwa amanye amagciwane kanye nesikhunta.

ILactoferrin nayo ibonakala ibandakanyeka emthethweni wokusebenza kwethambo (i-myelopoiesis), futhi kubonakala sengathi ikwazi ukukhulisa uhlelo lokuvikela izivikeli mzimba (immune system).

 

Imiphumela emibi ye-Lactoferrin

I-Lactoferrin powder iphephile ngamanani asetshenziswe ekudleni. Ukudla amanani aphakeme e-lactoferrin obisini lwenkomo kungahle futhi kuphephe kuze kube unyaka. I-lactoferrin yabantu eyenziwe ngelayisi elicutshungulwe ngokukhethekile ibonakala iphephile kuze kube yizinsuku eziyi-14. I-Lactoferrin ingadala isifo sohudo. Ngezilinganiso eziphakeme kakhulu, ukuqubuka kwesikhumba, ukulahlekelwa isifiso sokudla, ukukhathala, ukugodola nokuqunjelwa kubikiwe.

 

I-Lactoferrin powder kusebenzisa kanye nesicelo

IMILIKI EFANELE NE-LACTOFERRIN

Ezinganeni ezisanda kuzalwa ezisindayo, ubisi lwezinsana olucebiswe nge-lactoferrin (enama-probiotic noma ngaphandle kwayo) kunciphisa ingozi yokubambezeleka kwe-septicemia (ibhaktheriya noma isikhunta).

Ukuhlaziywa okujulile kwemiphumela kubonise ukuthi i-bovine lactoferrin inciphise ukutheleleka esikhundleni sokuvimbela isikhunta ukuthi singasakazeki. Lokhu kuphakamisa ukuthi i-lactoferrin iyakwazi ukuvikela ukutheleleka ngefungus ukuthi ingangeni kwisifo se-systemic.

I-Bovine lactoferrin ingangena ekuvinjelweni kwegazi-kwengqondo nge-receptors ethize, futhi ithuthukise i-neuroprotection, i-neurodevelopment kanye namakhono okufunda ezilwaneni ezincelisayo.

 

Izikhombo:

• U-Barrington K et al, Isilingo se-Lacuna: isivivinyo sokushayela izindiza esilawulwa ngendlela engakhethi eyimpumputhe yokufakwa kwe-lactoferrin enganeni ebaluleke kakhulu ngaphambi kokuzalwa, uJ. Perinatol. 2016 Aug; 36 (8): 666-9.
• Lauterbach R et al., Lactoferrin - i-glycoprotein yamandla amakhulu okwelapha, i-Dev Period Med. 2016 Ephreli-Jun; 20 (2): 118-25.
• I-autophagy elawulwa yi-Nbr1 ku-Lactoferrin-indased osteoblastic umehluko. UZhang Y, Zhang ZN, uLi N, uZhao LJ, u-Xue Y, u-Wu HJ, uLou JM. I-Biosci Biotechnol Biochem. 2020 Mar
• Umphumela we-Dose of Bovine Lactoferrin Forform on Iron Metabolism of Anemic Infants. I-Chen K, Zhang G, Chen H, Cao Y, Dong X, Li H, Liu C. J Nutr Sci Vitaminol (Tokyo). 2020
• I-Lactoferrin: Umdlali Obucayi ku-Neonatal Host Defense. UTelang S et al. Ama-Nutrients. (2018)
• Indima ye-Lactoferrin e-Neonates kanye nezinsana: Isibuyekezo. Manzoni P et al. NguJ J Perinatol. (2018)
• I-enteral lactoferrin isengezo sokuvimbela i-sepsis kanye ne-necrotizing enterocolitis ezinganeni ezisengaphambili. UPammi M et al. I-Cochrane Database SystRev Rev (2017)
• Yiziphi Izinzuzo Zokulekelelwa Kwe-Lactoferrin Zabantu Abadala Nabancane?

 

---