I-Lactoperoxidase (9003-99-0) ividiyo

I-Lactoperoxidase (9003-99-0) Siziqu

Igama Product	I-Lactoperoxidase (9003-99-0)
Igama leKhemikhali	I-Peroxidase; I-LPO
Brand NAme	N / A
I-Drug Class	N / A
CAS Inombolo	9003-99-0
InChIKey	N / A
I-molecular Fi-ormula	N / A
I-molecular Weziyisishiyagalombili	I-78 kDa
IMisa ye-Monoisotopic	N / A
Iphuzu lokubilisa	N / A
Fukuvuselela kabusha Pi-oint	N / A
I-Half Half-Life	N / A
Color	nsundu
Sukufaneleka	I-H2O: inyibilika
Sukuhlushwa Tukushisa	I-Lyophilised powder ingagcinwa ngo--20 ° C. Ihlala izinyanga eziyi-12 ngo-20 ° C.
Aukuphikisana	N / A

I-Lactoperoxidase (9003-99-0) Ukubuka konke

I-Lactoperoxidase iyi-enzyme etholakala ngokwemvelo ubisi olwaziwa ukuthi lunezakhiwo ze-antimicrobial ne-antioxidant. Ngokusho kocwaningo olushicilelwe kwiJustice of Applied Microbiology, inezakhi ze-antibacterial eziwusizo esikhunjeni futhi zingasusa amabhaktheriya abangela induna. I-Lactoperoxidase nayo iyingxenye ebalulekile ekuhlanganiseni kwezithako (i-LPO, ushukela, i-glucose oxidase (GO), iodide ne-thiocyanate) esetshenziselwa ukuvikela ama-yeast, isikhunta, amagciwane kanye namagciwane ekukhuleni kwezimonyo neminye imikhiqizo yobuhle (Umthombo).

Kuyini I-Lactoperoxidase ?

I-Lactoperoxidase iyi-glycoprotein enomsebenzi omelana ne-microbial, isetshenziswa njengesithako sokuqina ukusiza ukuthuthukisa ukwakheka kokuqina nempilo yeshalofu yempilo. Kuyenzeka ngokwemvelo ebisini.

Ucwaningo lwesayensi luveze ukuthi i-Lactoperoxidase, i-enzyme engokwemvelo obisini olungavuthiwe, ibangela ukusabela kwamakhemikhali kwe-thiocyanate, nayo etholakala ngokwemvelo obisini, lapho kukhona i-hydrogen peroxide. Isakhi esiphumela sinomphumela we-bacteriostatic kumabhakithiliya amaningi ngisho nomphumela we-bactericidal kwamanye amagciwane, njenge-Escherichia coli.

Uhlelo lwe-Lactoperoxidase (LP-s) ngomunye womndeni okhulayo wama-biostatics ongaba nemiphumela ezuzisayo ekusebenzeni kobisi ngokwelula ishalofu-impilo futhi uthuthukise ikhwalithi yobisi oluqoqwe noma lugcinwe.

Ngo-2005 i-FAO kanye ne-WHO yaqhuba umhlangano wezobuchwepheshe ngezinzuzo nezingozi ezingaba khona ze-LP-s zokugcinwa kobisi oluluhlaza, ukuze inikeze izeluleko zesayensi kuCodex Alimentarius.

Lo msebenzi futhi uphendula nezinkinga zamazwe angamalungu mayelana nokusetshenziswa kwe-LP-s, ikakhulukazi ngokubheka ukuholwa kweCodex yamanje, okukhawulela ukusetshenziswa kwe-LP-s yokulondolozwa kobisi okuluhlaza kumikhiqizo yobisi nemikhiqizo yobisi engeke idayiswe kwamanye amazwe.

Imiphumela emibi ye-Lactoperoxidase

Ayikho imiphumela emibi evela ekusetshenzisweni kwemikhiqizo equkethe i-Lactoperoxidase ekugxileni okujwayelekile.

I-Lactoperoxidase powder kusebenzisa kanye nesicelo

I-Lactoperoxidase yi-ejenti ephumelelayo ye-antimicrobial. Ngenxa yalokho, ukusetshenziswa kwe-lactoperoxidase powder kuyatholakala ekulondolozeni ukudla, izimonyo nezixazululo zamehlo. Ngaphezu kwalokho, i-lactoperoxidase ithole uhlelo lokusebenza ekwelashweni kwamazinyo nokulimala. Ekugcineni i-lactoperoxidase ingathola ukusetshenziswa njengama-anti-tumor kanye nama-anti viral agents.

imikhiqizo yobisi

I-Lactoperoxidase yi-ejenti ephumelelayo ye-antimicrobial futhi isetshenziswa njenge-ejenti ye-antibacterial ekwehliseni ama-microflora we-bacterium kwimikhiqizo yobisi nemikhiqizo yobisi. Ukwenza kusebenze kohlelo lwe-lactoperoxidase ngokungezelelwa kwe-hydrogen peroxide ne-thiocyanate kukhulisa impilo eshalofini lebisi eliluhlaza esiqandisiwe. Kuyinto emelana nokushisa ngokufanele futhi isetshenziswa njengesinkomba sokusetshenziswa ngokweqile kobisi.

Ukunakekelwa komlomo

Isistimu ye-lactoperoxidase kuthiwa ilungele ukwelashwa kwe-gingivitis neparadentosis. I-Lactoperoxidase isetshenziswe emazinyweni noma emgomeni ukuze kuncishiswe ama-bacterium omlomo futhi ngenxa yalokho i-acid ekhiqizwa yilawo magciwane.

Cosmetics

Inhlanganisela ye-lactoperoxidase, i-glucose, i-glucose oxidase (NKULUNKULU), iodide ne-thiocyanate kuthiwa iyasebenza ekugcinweni kwezimonyo.

Umdlavuza kanye nokutheleleka ngegciwane

Ama-antibody conjugates e-glucose oxidase ne-lactoperoxidase atholakele esebenza ekubulaleni amaseli e-tumor in vitro. Ngaphezu kwalokho, ama-macrophages adalulwe lactoperoxidase akhuthazelwa ukubulala amaseli womdlavuza.

I-hyperoocyanite ekhiqizwa yiPeroxidase inhibits herpes simplex virus kanye negciwane lesifo sokugonywa komuntu.

Izikhombo:

• Ukubaluleka kwe-Lactoperoxidase System ku-Oral Health: Ukusebenza kanye nokusebenza kahle kwemikhiqizo ye-Oral Hygiene. Magacz M, Kędziora K, Sapa J, Krzyściak W. Int J Mol Sci. 2019 Mar 21
• Ukusebenza kahle kwe-antibacterial yomlomo wegwebu namandla ayo okususa i-biofilms. UJones SB, West NX, Nesmiyanov PP, Krylov SE, Klechkovskaya VV, Arkharova NA, Zakirova SA. BDJ Vula. 2018 Sep 27;
• Ukusebenza kahle komtholampilo kwamazinyo okuxubha avela enzyme. Isivivinyo somtholampilo esilawulwa ngamehlo. Llena C, Oteo C, Oteo J, Amengual J, Forner L. J Dent. 2016 Jan
• Ukunakekelwa komlomo kunganciphisa inyumoniya kubantu abadala abondlekile nge-tube: isifundo sokuqala. UMaeda K, Akagi J.Dysphagia. 2014 Oct; 29

---