I-NADH 2Na (606-68-8)

Mashi 15, 2020
SKU: 129311-55-3

I-NADH iyinhlobo ye-enzyme ye-nicotinamide adenine dinucleotide (NAD), ifomu le-coenzyme elisebenzayo lenhlanganisela nevithamini B3 ……….

 


Isimo: Ekukhiqizeni kweMisa
Izakhiwe futhi zenziwe ngokwezifiso zitholakalayo
Umthamo: 1277kg / inyanga

Ividiyo yeNADH 2Na (606-68-8)

Beta-Nicotinamide adenine dinucleotide disodium usawoti (NADH 2Na) Imininingwane

Igama Product I-Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)
Igama leKhemikhali I-NADH (usawoti we-disodium); I-Disodium nicotinamide adenine dinucleotide; i-eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Usawoti; I-Nicotinamide adenine dinucleotide, incishisiwe;
CAS Inombolo 606-68-8
InChIKey I-QRGNQKGQENGQSE-WUEGHLCSSA-L
SMILE C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Formula Yamamolekhula C21H27N7Na2O14P2
isisindo Yamamolekhula 709.4
IMisa ye-Monoisotopic I-709.088661 g / mol
I-Melting Point I-140-142 ℃
Color Yellow
Sithempeli le-torage I-2-8 ℃
solubility I-H2O: 50 mg / mL, kucace kuze kucace, kuphuzi
Isicelo Umuthi; ukudla nezithako zokudla okunempilo;

 

Yini i-Beta-Nicotinamide adenine dinucleotide disodium usawoti (NADH 2Na)?

I-NADH iyinhlobo ye-enzyme ye-nicotinamide adenine dinucleotide (NAD), ifomu le-coenzyme elisebenzayo le-compound ne-vitamin B3. I-NADH (b-Nicotinamide adenine dinucleotide) I-Disodium Salt, encishisiwe, eyaziwa nangokuthi yiNicotinamide adenine dinucleotide, iyinhlangano eyi-coenzyme ekuphendukeni kwe-redox. Imisebenzi yayo njengomnikeli ovuselelayo womnikeli we-elektroni ezinkambisweni zemvelo kufaka phakathi i-glycolysis, β-oxidation kanye nomjikelezo we-citric acid (umjikelezo weKrebs, umjikelezo we-TCA) Usawoti we-NADH disodium ubuye ubambe iqhaza emicimbini esayina amaseli, ngokwesibonelo njenge-substrate ye-poly (ADP-ribose) polymerases (PARPs) ngesikhathi sokuphendula ngomonakalo we-DNA. Njengosawoti we-disodium we-NADH, usetshenziselwa izithako zokudla nezokudla ekwelapheni isifo sikaParkinson, isifo sokukhathala okungamahlalakhona, isifo i-Alzheimer's kanye nezifo zenhliziyo.

 

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) izinzuzo

Njenge-coenzyme ye-oxidoreductases, usawoti we-NADH disodium udlala indima ebalulekile ekukhiqizeni amandla omzimba.

- Usawoti we-NADH disodium ungaholela ekucaceni okungcono kwengqondo, ukuqapha, ukugxila, nenkumbulo. Kungakhuphula ukuqina kwengqondo futhi kungakhuphula imizwa. Ingakhuphula amazinga amandla emzimbeni futhi ithuthukise imetabolism, amandla obuchopho nokukhuthazela.

- Siza abantu abanokucindezeleka kwemitholampilo, umfutho wegazi ophakeme noma i-cholesterol ephezulu;

- Thuthukisa ukusebenza kwezemidlalo;

- Ukubambezela inqubo yokuguga nokugcina ubuqotho bamaseli ezinzwa ukusekela uhlelo lwezinzwa;

- Angalapha isifo sikaParkinson, athuthukise ukusebenza kwama-neurotransmitters ebuchosheni beziguli ezinesifo sikaParkinson, anciphise ukukhubazeka ngokomzimba nezidingo zezidakamizwa;

- Therap chronic fatigue syndrome (CFS), isifo i-Alzheimer nesifo senhliziyo;

- Vikela emiphumeleni emibi yomuthi we-AIDS obizwa nge-zidovudine (AZT);

- Phikisa imiphumela yotshwala esibindini;

- I-Jet lag

 

I-Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) okuqhamuka uma udla imishanguzo:

Njengamanje, usawoti we-NADH usawoti ubonakala ephephile kubantu abaningi uma usetshenziswa ngendlela efanele nangesikhashana esifushane, kuze kube ngamaviki ayi-12. Iningi labantu alitholi imiphumela emibi lapho lithatha inani elinconywayo usuku ngalunye, okuyi-10 mg.

Noma kunjalo, akukho datha eyanele ngokusetshenziswa kwe-NADH disodium usawoti ngesikhathi sokukhulelwa nokuncelisa., Ngakho-ke kufanele bahlale ngasohlangothini oluphephile futhi bagweme ukusetshenziswa.

 

Izikhombo:

  • IBirkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - indlela entsha yokwelapha isifo sikaParkinson. Ukuqhathaniswa kwesicelo somlomo nesobuzali. I-Acta Neurol Scand Suppl 1993; 146: 32-5.
  • UBudavari S, u-ed. Inkomba ye-Merck. Umhla ka-12. I-Whitehouse Station, NJ: Merck & Co, Inc., ngo-1996.
  • UBushehri N, Jarrell ST, uLieberman S, et al. Ukuncipha komlomo okuncishiswe i-B-nicotinamide adenine dinucleotide (NADH) kuthinta umfutho wegazi, i-lipid peroxidation, kanye nephrofayili ye-lipid kumagundane anegazi (SHR). UGeriatr Nephrol Urol 1998; 8: 95-100.
  • UBushehri N, Jarrell ST, uLieberman S, et al. Ukuncipha komlomo okuncishiswe i-B-nicotinamide adenine dinucleotide (NADH) kuthinta umfutho wegazi, i-lipid peroxidation, kanye nephrofayili ye-lipid kumagundane anegazi (SHR). UGeriatr Nephrol Urol 1998; 8: 95-100.
  • UCastro-Marrero J, uCordero MD, uSegundo MJ, et al. Ngabe i-coenzyme Q10 yokuhlanganisa ngomlomo kanye ne-NADH yokungezelela ikhulisa ukukhathala kanye nemingcele ye-biochemical ku-fatigue syndrome? I-Antioxid Redox Signal 2015; 22 (8): 679-85.
  • UDizdar N, Kagedal B, Lindvall B. Ukwelashwa kwesifo sikaParkinson nge-NADH. I-Acta Neurol Scand 1994; 90: 345-7.